Compile Data Set for Download or QSAR
maximum 50k data
Found 1027 of ki for UniProtKB: Q9R0C9
LigandPNGBDBM50170654((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  0.0980nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  0.0980nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374600(CHEMBL272899)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)-pentazocine from opioid sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50494706(CHEMBL3093268)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50000066((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]-NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532486(CHEMBL4564992)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532486(CHEMBL4564992)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM312233(US9604926, Compound AZ-66 | US9724435, Compound AZ...)
Affinity DataKi:  0.310nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  0.340nMAssay Description:Tested for its binding affinity towards sigma-1 site in rat brain, using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50265433(1-Isobutyl-4-phenylpiperidine-4-carbonitrile | CHE...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50265436(1-Phenylpropyl-4-phenylpiperidine-4-carbonitrile |...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50058023(4-(4-Bromo-phenoxymethyl)-1-(3-fluoro-propyl)-pipe...)
Affinity DataKi:  0.380nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50265434(1-Benzyl-4-phenylpiperidine-4-carbonitrile | CHEMB...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50343621(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-nitrobenzyl)pi...)
Affinity DataKi:  0.430nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532506(CHEMBL4536431)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532518(CHEMBL4440420)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532508(CHEMBL4471576)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532518(CHEMBL4440420)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50058007(1-Cyclopropylmethyl-4-(4-iodo-phenoxymethyl)-piper...)
Affinity DataKi:  0.5nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532508(CHEMBL4471576)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532506(CHEMBL4536431)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50064172(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in rat liver membranes incubated for 60 mins in presence of [3H]DTG by radioactivity metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374600(CHEMBL272899)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma1 receptor in rat liver homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50494707(CHEMBL3093270)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259004(1'-[4-Fluorobenzyl]-3H-spiro[[2]benzofuran-1,4'pip...)
Affinity DataKi:  0.580nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM312168(US9604926, Compound CM-172 | US9724435, Compound C...)
Affinity DataKi:  0.580nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50058010(4-(4-Bromo-phenoxymethyl)-1-cyclopropylmethyl-pipe...)
Affinity DataKi:  0.600nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532502(CHEMBL4538923)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532502(CHEMBL4538923)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50058012(4-[1-(4-Fluoro-benzyl)-piperidin-4-ylmethoxy]-benz...)
Affinity DataKi:  0.760nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50343619(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-bromobenzyl)pi...)
Affinity DataKi:  0.780nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50432550(CHEMBL2347001)
Affinity DataKi:  0.790nMAssay Description:Displacement of (+)-[3H]pentazocine from rat brain sigma1 receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532512(CHEMBL4539105)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]Pentazocine from rat sigma 1 receptor in rat PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50343620(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-iodobenzyl)pip...)
Affinity DataKi:  0.800nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532512(CHEMBL4539105)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50047016(1-(4-Fluoro-phenyl)-4-[4-hydroxy-4-(3-trifluoromet...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50058008(1-(2-Fluoro-ethyl)-4-(4-iodo-phenoxymethyl)-piperi...)
Affinity DataKi:  0.840nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50343618(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-fluorobenzyl)p...)
Affinity DataKi:  0.850nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50058011(4-(3-Bromo-phenoxymethyl)-1-cyclopropylmethyl-pipe...)
Affinity DataKi:  0.880nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
LigandPNGBDBM50532507(CHEMBL4593797)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50532507(CHEMBL4593797)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50343622(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-methylbenzyl)-...)
Affinity DataKi:  0.910nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199806(CHEMBL3944169 | US10913711, Compound 9a | US115550...)
Affinity DataKi:  0.940nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM312167(US9604926, Compound CM-171 | US9724435, Compound C...)
Affinity DataKi:  0.940nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50199806(CHEMBL3944169 | US10913711, Compound 9a | US115550...)
Affinity DataKi:  0.940nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
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