Compile Data Set for Download or QSAR
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Report error Found 3100 of ki for UniProtKB: Q99720
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50398057(CHEMBL2181924)
Affinity DataKi:  0.00250nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50170654((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
Affinity DataKi:  0.0100nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50146585(CHEMBL3763396)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi:  0.0360nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50170652((2R,6S)-2,6-Dimethyl-4-tridecyl-morpholine | CHEMB...)
Affinity DataKi:  0.0400nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50038707(1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(...)
Affinity DataKi:  0.0500nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50038707(1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(...)
Affinity DataKi:  0.0500nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415166(CHEMBL578825)
Affinity DataKi:  0.0525nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415165(CHEMBL570795)
Affinity DataKi:  0.0575nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415164(CHEMBL570529)
Affinity DataKi:  0.0661nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50144508(4-Methyl-1-(5-phenyl-pentyl)-piperidine | CHEMBL30...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  0.0800nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50170654((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor expressed in Saccharomyces cerevisiae WA0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415163(CHEMBL571418)
Affinity DataKi:  0.0891nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50144518(1-(5,5-Diphenyl-pentyl)-4-methyl-piperidine | CHEM...)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415162(CHEMBL572294)
Affinity DataKi:  0.0977nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415161(CHEMBL570067)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50144512(1-(5,5-Diphenyl-pent-4-enyl)-4-methyl-piperidine |...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50065136(CHEMBL81455 | N-(2-Azepan-1-yl-ethyl)-4-iodo-N-met...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041259(CHEMBL19355 | Phenethyl-(5-phenyl-pentyl)-amine)
Affinity DataKi:  0.170nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041259(CHEMBL19355 | Phenethyl-(5-phenyl-pentyl)-amine)
Affinity DataKi:  0.170nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50000066((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50065134(CHEMBL309983 | N-(2-Azepan-1-yl-ethyl)-4-bromo-N-m...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041268(Benzyl-methyl-(5-phenyl-pentyl)-amine | CHEMBL1931...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50170636(2-[4-(3-Dibenzo[b,f]azepin-5-yl-propyl)-piperazin-...)
Affinity DataKi:  0.200nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.200nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50415160(CHEMBL571659)
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50145029(1-Cyclohexyl-4-(4-naphthalen-1-yl-butyl)-piperazin...)
Affinity DataKi:  0.220nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041246(CHEMBL19544 | Methyl-phenethyl-(5-phenyl-pentyl)-a...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041246(CHEMBL19544 | Methyl-phenethyl-(5-phenyl-pentyl)-a...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041277((5-Cyclohexyl-pentyl)-dimethyl-amine | CHEMBL20036)
Affinity DataKi:  0.260nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50000068(CHEMBL142700 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50038717(1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 3-(...)
Affinity DataKi:  0.270nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041257((5-Phenyl-pentyl)-(3-phenyl-propyl)-amine | CHEMBL...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041275(CHEMBL20348 | Methyl-(5-phenyl-pentyl)-propyl-amin...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50037480((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50159013(3-(4-Benzyl-piperazin-1-ylmethyl)-3,4-dihydro-2H-n...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50159021(1-Benzyl-4-chroman-3-ylmethyl-piperazine | 1-benzy...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50159018(1-Benzyl-4-chroman-2-ylmethyl-piperazine | 1-benzy...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50145014(1-Cyclohexyl-4-(5-methoxy-1,2,3,4-tetrahydro-napht...)
Affinity DataKi:  0.310nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50000776(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50068455(CHEMBL342809 | {4-Oxo-4-[4-(3-phenyl-propyl)-piper...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity was tested against sigma-1 receptor in guinea brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50041243(Benzyl-(5-phenyl-pentyl)-amine | CHEMBL19315)
Affinity DataKi:  0.320nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.330nMAssay Description:Tested for [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity against [3H]-3-PPP labelled sigma sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50128107(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  0.340nMAssay Description:Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50145019(1-Cyclohexyl-4-[3-(6-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.360nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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