Compile Data Set for Download or QSAR
Found 890 of ic50 for UniProtKB: P19793
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276467(5-Chloro-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276124(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276506(2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276535(2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]metho...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276537(2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]metho...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276538(5-Ethyl-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4-...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276540(2-[[1-(4-Fluoro-3-methyl-phenyl)triazol-4-yl]metho...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276542(5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276133(2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276134(2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276139(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276144(2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276468(2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50129731(7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phenyl]...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against Retinoic acid receptor RXR-alpha antagonist was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276109(2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50135453((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-3-isopropyl-...)
Affinity DataIC50:  1.90nMAssay Description:In vitro agonist efficacy against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276469(2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276536(5-Chloro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276541(5-Fluoro-2-[[1-(4-fluoro-3-methyl-phenyl)triazol-4...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276363(2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]me...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276121(5-Chloro-2-[[1-[4-chloro-3-(difluoromethoxy)phenyl...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276125(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276312(4,5-Dimethyl-2-[[1-(m-tolyl)triazol-4-yl]methoxy]p...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276114(2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276115(2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-...)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50135460((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-4'-fluoro-5-...)
Affinity DataIC50:  2.20nMAssay Description:In vitro anatagonist activity against RXR alpha in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276594(2-[[1-[4-Chloro-3-(1,1-difluoroethyl)phenyl]triazo...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276119(2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276466(5-(Difluoromethoxy)-2-[[1-[3-(difluoromethyl)-4-fl...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276554(5-Bromo-2-[[1-[3-(difluoromethoxy)-4-fluoro-phenyl...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276569(4-(Azetidin-1-yl)-2-[[1-[3-(difluoromethoxy)-4-flu...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276367(2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]me...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276369(2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]me...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276459(5-Bromo-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl]...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276340(5-Chloro-2-[[1-[3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276355(5-Chloro-2-[[1-[3-(1,1-difluoroethyl)phenyl]triazo...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276135(2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276140(5-Chloro-2-[[1-[4-chloro-3-(difluoromethyl)phenyl]...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276142(5-Chloro-2-[[1-[3-(difluoromethyl)-4-fluoro-phenyl...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276154(5-Chloro-2-[[1-[3-(difluoromethoxy)-4-fluoro-pheny...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276156(2-[[1-[3-(Difluoromethoxy)-4-fluoro-phenyl]triazol...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276174(2-[[1-[4-Fluoro-3-(trifluoromethyl)phenyl]triazol-...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276178(2-[[1-(3-Bromo-4-fluoro-phenyl)triazol-4-yl]methox...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276681(2-[[1-(3-Chloro-4-fluoro-phenyl)triazol-4-yl]metho...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50135450((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-2'-fluoro-5-...)
Affinity DataIC50:  3.10nMAssay Description:In vitro agonist efficacy against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50135452((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-5-furan-2-yl...)
Affinity DataIC50:  3.60nMAssay Description:In vitro agonistic activity against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50135462((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3'-fluoro-5-...)
Affinity DataIC50:  3.90nMAssay Description:Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276692(2-[[1-[4-chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276123(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM276503(5-Ethoxy-2-[[1-[4-fluoro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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