Compile Data Set for Download or QSAR
Found 1 of affinity data for UniProtKB/TrEMBL: Q9EQY0
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Mus musculus)

Curated by ChEMBL
LigandPNGBDBM160445(US9040714, 167 | US9693992, 167)
Show SMILES COc1cc2c(C)c(CC(=O)N3CCOCC3)c(=O)oc2c(C=O)c1O
Show InChI InChI=1S/C18H19NO7/c1-10-11-7-14(24-2)16(22)13(9-20)17(11)26-18(23)12(10)8-15(21)19-3-5-25-6-4-19/h7,9,22H,3-6,8H2,1-2H3
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse IRE1 assessed as reduction in XBP1 splicing using 5'-Alexa Fluor 647-CAUGUCCGCAGCGCAUG-BHQ1-3' as substrate preincubated for 30 m...More data for this Ligand-Target Pair