Compile Data Set for Download or QSAR
Found 4 of ic50 for UniProtKB: P28335
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Sunshine Lake Pharma Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50573968(CHEMBL4851044)
Show SMILES CN1CCC(CC1)=C(F)c1cccc(NC(=O)c2c(F)cc(F)cc2F)n1
Show InChI InChI=1S/C19H17F4N3O/c1-26-7-5-11(6-8-26)18(23)15-3-2-4-16(24-15)25-19(27)17-13(21)9-12(20)10-14(17)22/h2-4,9-10H,5-8H2,1H3,(H,24,25,27)
Affinity DataIC50: 7.06E+3nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Sunshine Lake Pharma Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM264118(3-(4-(4-(4-(5-oxo-1,6-naphthyridin-6(5H)-yl)phenyl...)
Show SMILES O=c1n(ccc2ncccc12)-c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C31H30N6O/c32-21-23-6-11-29-28(20-23)24(22-34-29)4-1-2-14-35-16-18-36(19-17-35)25-7-9-26(10-8-25)37-15-12-30-27(31(37)38)5-3-13-33-30/h3,5-13,15,20,22,34H,1-2,4,14,16-19H2
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT2c (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Sunshine Lake Pharma Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM264120(3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...)
Show SMILES O=c1n(ccc2occc12)-c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C30H29N5O2/c31-20-22-4-9-28-27(19-22)23(21-32-28)3-1-2-12-33-14-16-34(17-15-33)24-5-7-25(8-6-24)35-13-10-29-26(30(35)36)11-18-37-29/h4-11,13,18-19,21,32H,1-3,12,14-17H2
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT2c (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Sunshine Lake Pharma Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM264119(3-(3-(4-(4-(5-oxo-1,6-naphthyridin-6(5H)-yl)phenyl...)
Show SMILES O=c1n(ccc2ncccc12)-c1ccc(cc1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C30H28N6O/c31-20-22-5-10-28-27(19-22)23(21-33-28)3-2-13-34-15-17-35(18-16-34)24-6-8-25(9-7-24)36-14-11-29-26(30(36)37)4-1-12-32-29/h1,4-12,14,19,21,33H,2-3,13,15-18H2
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT2c (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed