Compile Data Set for Download or QSAR
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Report error Found 256 of affinity data for UniProtKB/TrEMBL: P04156
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357271(2-(((1s,4s)-4-((5- (cyanomethylthio)-3,4- diphenyl...)
Affinity DataIC50:  20nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357270(2-(((1s,4s)-4-((5- (methylthio)-4-(5- methylthioph...)
Affinity DataIC50:  28nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357273(2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-3,4- diphe...)
Affinity DataIC50:  70nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM47242(4-bromanyl-2-methyl-7,8,9,10-tetrahydro-6H-cyclohe...)
Affinity DataIC50:  141nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM95259(3,4-dimethyl-2-(4-methylphenyl)-2,6-dihydro-7H-pyr...)
Affinity DataIC50:  143nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357274(2-(((1s,4s)-4-((4-(5- fluoropyridin-3-yl)-5- (meth...)
Affinity DataIC50:  220nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114355(2-(4-ethoxyphenyl)-3,4-dimethyl-2,6-dihydro-7H-pyr...)
Affinity DataIC50:  321nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM95288(6-fluoranyl-3-[(2-methoxyphenyl)methyl]-2-sulfanyl...)
Affinity DataIC50:  412nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114360(2-methoxy-5-[[4-(4-oxidanylidenecyclohexa-2,5-dien...)
Affinity DataIC50:  759nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM47306(2-[(5-cyano-4-oxidanylidene-6-thiophen-2-yl-1H-pyr...)
Affinity DataIC50:  876nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114329(Cyclohexanecarboxylic acid N'-[2-(2-propyl-qui...)
Affinity DataIC50:  896nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114392(2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfany...)
Affinity DataIC50:  908nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM40943((2-Isopropyl-quinazolin-4-ylsulfanyl)-acetic acid ...)
Affinity DataIC50:  910nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM42858(3-(2-methylquinazolin-4-yl)sulfanylpropanoic acid ...)
Affinity DataIC50:  915nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM41001(2-(2-Isopropyl-quinazolin-4-ylsulfanyl)-N-(5-methy...)
Affinity DataIC50:  936nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM42605(MLS000073796 | N-(5-Methyl-isoxazol-3-yl)-2-(2-pro...)
Affinity DataIC50:  1.01E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM42791(2-[(4-fluorobenzyl)thio]-4-(2-furyl)-6-oxo-1,6-dih...)
Affinity DataIC50:  1.03E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM47311(2-[(4-chlorobenzyl)sulfanyl]-6-oxo-4-(2-thienyl)-1...)
Affinity DataIC50:  1.05E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114306((2-Ethyl-quinazolin-4-ylsulfanyl)-acetic acid ethy...)
Affinity DataIC50:  1.08E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM41000((2-Isopropyl-quinazolin-4-ylsulfanyl)-acetic acid ...)
Affinity DataIC50:  1.08E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114431(5-[[(4-bromo-2,5-dimethyl-pyrazole-3-carbonyl)amin...)
Affinity DataIC50:  1.16E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM41064(Cyclohexanecarboxylic acid N'-[2-(2-ethyl-quin...)
Affinity DataIC50:  1.18E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114417(6-bromanyl-2-(5-ethylthiophen-2-yl)-3-methyl-quino...)
Affinity DataIC50:  1.25E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114379(2-[(2-phenyl-4-quinazolinyl)thio]acetic acid methy...)
Affinity DataIC50:  1.31E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114425(4-Methyl-benzoic acid N'-[2-(2-ethyl-quinazoli...)
Affinity DataIC50:  1.36E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM54184(6,8-bis(bromanyl)-2-methyl-quinolin-3-ol | 6,8-dib...)
Affinity DataIC50:  1.36E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM66153(6,8-bis(bromanyl)-4-piperidin-1-yl-quinazoline | 6...)
Affinity DataIC50:  1.38E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114443(2-(1-bromanylnaphthalen-2-yl)oxy-N-(5-methyl-1,2-o...)
Affinity DataIC50:  1.39E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM66192(6-bromanyl-2-thiophen-2-yl-quinoline-4-carboxylic ...)
Affinity DataIC50:  1.41E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM78382(6-bromo-5-hydroxy-2-phenyl-3-benzofurancarboxylic ...)
Affinity DataIC50:  1.44E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM78637(1,5-dihydropyrimid[5,4-b]indole-4-thione | 1,5-dih...)
Affinity DataIC50:  1.50E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114381(4-methoxy-N'-[1-oxo-2-[(2-propyl-4-quinazolinyl)th...)
Affinity DataIC50:  1.52E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM42635(2-(2-quinolinylthio)propanoic acid | 2-(2-quinolyl...)
Affinity DataIC50:  1.56E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114447(2-(5-bromanylnaphthalen-1-yl)carbonylbenzoic acid ...)
Affinity DataIC50:  1.57E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM42714(MLS000089894 | N-(3-chlorophenyl)-2-[[5-cyano-6-(2...)
Affinity DataIC50:  1.69E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM53214(2,5-dihydro-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114440(MLS002165637 | N-(5-methyl-1,2-oxazol-3-yl)-2-(2-t...)
Affinity DataIC50:  1.70E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114361(MLS000677348 | N'-[2-(2-ethylquinazolin-4-yl)sulfa...)
Affinity DataIC50:  1.72E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114330((2-Phenyl-quinazolin-4-ylsulfanyl)-acetic acid eth...)
Affinity DataIC50:  1.73E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM41062(2-(2-Isopropyl-quinazolin-4-ylsulfanyl)-N-(5-methy...)
Affinity DataIC50:  1.83E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114384(2-[(2-phenyl-4-quinazolinyl)thio]propanoic acid et...)
Affinity DataIC50:  1.84E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114331(2-(2-Ethyl-quinazolin-4-ylsulfanyl)-1-phenothiazin...)
Affinity DataIC50:  1.84E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114305(2,6-Diamino-4-p-tolyl-4H-thiopyran-3,5-dicarbonitr...)
Affinity DataIC50:  1.86E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114319(MLS000555430 | SMR000147147 | Sodium; 2-(quinolin-...)
Affinity DataIC50:  1.88E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM42607(2-(6-Bromo-quinazolin-4-ylamino)-4-methylsulfanyl-...)
Affinity DataIC50:  1.91E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM66190(2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-...)
Affinity DataIC50:  1.92E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114311(1-[1-[4-amino-6-(N-phenylanilino)-1,3,5-triazin-2-...)
Affinity DataIC50:  1.92E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114322(3-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)sulf...)
Affinity DataIC50:  1.93E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114332(Isobutyric acid N'-[2-(2-ethyl-quinazolin-4-yl...)
Affinity DataIC50:  1.93E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM114333((6-Fluoro-2-phenyl-quinazolin-4-ylsulfanyl)-acetic...)
Affinity DataIC50:  1.97E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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