Compile Data Set for Download or QSAR
Found 23 of affinity data for UniProtKB/TrEMBL: Q13191
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570684(CHEMBL4872230)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C30H43N6O13P/c1-16(37)25(34-27(42)21(32-17(2)38)15-18-7-9-19(10-8-18)49-50(46,47)48)30(45)36-14-4-6-23(36)28(43)33-20(11-12-24(39)40)29(44)35-13-3-5-22(35)26(31)41/h7-10,16,20-23,25,37H,3-6,11-15H2,1-2H3,(H2,31,41)(H,32,38)(H,33,43)(H,34,42)(H,39,40)(H2,46,47,48)/t16-,20+,21+,22+,23+,25+/m1/s1
Affinity DataIC50: 7.84E+3nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570682(CHEMBL4846771)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C39H56N9O18P/c1-19(33(40)56)42-36(59)27-6-4-14-47(27)38(61)24(12-13-30(52)53)45-37(60)28-7-5-15-48(28)39(62)32(20(2)49)46-35(58)25(16-22-8-10-23(11-9-22)66-67(63,64)65)44-29(51)18-41-34(57)26(17-31(54)55)43-21(3)50/h8-11,19-20,24-28,32,49H,4-7,12-18H2,1-3H3,(H2,40,56)(H,41,57)(H,42,59)(H,43,50)(H,44,51)(H,45,60)(H,46,58)(H,52,53)(H,54,55)(H2,63,64,65)/t19-,20+,24-,25-,26-,27-,28-,32-/m0/s1
Affinity DataIC50: 1.06E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570683(CHEMBL4853735)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CNC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C32H46N7O14P/c1-17(40)27(37-29(46)22(35-25(42)16-34-18(2)41)15-19-7-9-20(10-8-19)53-54(50,51)52)32(49)39-14-4-6-24(39)30(47)36-21(11-12-26(43)44)31(48)38-13-3-5-23(38)28(33)45/h7-10,17,21-24,27,40H,3-6,11-16H2,1-2H3,(H2,33,45)(H,34,41)(H,35,42)(H,36,47)(H,37,46)(H,43,44)(H2,50,51,52)/t17-,21+,22+,23+,24+,27+/m1/s1
Affinity DataIC50: 1.13E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570689(CHEMBL4867045)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C28H41N6O13P/c1-14(25(40)32-19(10-11-22(37)38)28(43)34-12-4-5-21(34)24(29)39)30-27(42)23(15(2)35)33-26(41)20(31-16(3)36)13-17-6-8-18(9-7-17)47-48(44,45)46/h6-9,14-15,19-21,23,35H,4-5,10-13H2,1-3H3,(H2,29,39)(H,30,42)(H,31,36)(H,32,40)(H,33,41)(H,37,38)(H2,44,45,46)/t14-,15+,19-,20-,21-,23-/m0/s1
Affinity DataIC50: 2.73E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570690(CHEMBL4874562)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C28H41N6O11P/c1-15(27(40)33-12-4-6-21(33)24(29)37)30-26(39)22-7-5-13-34(22)28(41)23(16(2)35)32-25(38)20(31-17(3)36)14-18-8-10-19(11-9-18)45-46(42,43)44/h8-11,15-16,20-23,35H,4-7,12-14H2,1-3H3,(H2,29,37)(H,30,39)(H,31,36)(H,32,38)(H2,42,43,44)/t15-,16+,20-,21-,22-,23-/m0/s1
Affinity DataIC50: 4.63E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570688(CHEMBL4858812)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C29H41N6O12P/c1-16(31-26(40)21(32-17(2)36)15-18-7-9-19(10-8-18)47-48(44,45)46)28(42)35-14-4-6-23(35)27(41)33-20(11-12-24(37)38)29(43)34-13-3-5-22(34)25(30)39/h7-10,16,20-23H,3-6,11-15H2,1-2H3,(H2,30,39)(H,31,40)(H,32,36)(H,33,41)(H,37,38)(H2,44,45,46)/t16-,20-,21-,22-,23-/m0/s1
Affinity DataIC50: 1.04E+5nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570686(CHEMBL4865503)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(N)=O
Show InChI InChI=1S/C25H36N5O12P/c1-13(31)21(25(38)30-11-3-4-19(30)24(37)28-17(22(26)35)9-10-20(33)34)29-23(36)18(27-14(2)32)12-15-5-7-16(8-6-15)42-43(39,40)41/h5-8,13,17-19,21,31H,3-4,9-12H2,1-2H3,(H2,26,35)(H,27,32)(H,28,37)(H,29,36)(H,33,34)(H2,39,40,41)/t13-,17+,18+,19+,21+/m1/s1
Affinity DataIC50: 3.99E+5nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570685(CHEMBL4858228)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C25H36N5O13P/c1-13(31)21(24(37)30-10-2-3-18(30)23(36)28-16(25(38)39)8-9-20(33)34)29-22(35)17(27-19(32)12-26)11-14-4-6-15(7-5-14)43-44(40,41)42/h4-7,13,16-18,21,31H,2-3,8-12,26H2,1H3,(H,27,32)(H,28,36)(H,29,35)(H,33,34)(H,38,39)(H2,40,41,42)/t13-,16+,17+,18+,21+/m1/s1
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570687(CHEMBL4849701)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C26H40N6O11/c1-13(33)21(30-23(40)15(28-14(2)34)7-9-19(35)36)26(43)32-12-4-6-18(32)24(41)29-16(8-10-20(37)38)25(42)31-11-3-5-17(31)22(27)39/h13,15-18,21,33H,3-12H2,1-2H3,(H2,27,39)(H,28,34)(H,29,41)(H,30,40)(H,35,36)(H,37,38)/t13-,15+,16+,17+,18+,21+/m1/s1
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) using FITC-DGpYPEPA-N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570693(CHEMBL4875389)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C31H47N6O13P/c1-16(2)14-22(28(43)34-21(11-12-25(40)41)31(46)37-13-5-6-24(37)27(32)42)35-30(45)26(17(3)38)36-29(44)23(33-18(4)39)15-19-7-9-20(10-8-19)50-51(47,48)49/h7-10,16-17,21-24,26,38H,5-6,11-15H2,1-4H3,(H2,32,42)(H,33,39)(H,34,43)(H,35,45)(H,36,44)(H,40,41)(H2,47,48,49)/t17-,21+,22+,23+,24+,26+/m1/s1
Affinity DataKd:  2.98E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570694(CHEMBL4870845)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C31H47N6O13P/c1-5-16(2)25(29(44)34-21(12-13-24(40)41)31(46)37-14-6-7-23(37)27(32)42)35-30(45)26(17(3)38)36-28(43)22(33-18(4)39)15-19-8-10-20(11-9-19)50-51(47,48)49/h8-11,16-17,21-23,25-26,38H,5-7,12-15H2,1-4H3,(H2,32,42)(H,33,39)(H,34,44)(H,35,45)(H,36,43)(H,40,41)(H2,47,48,49)/t16-,17+,21-,22-,23-,25-,26-/m0/s1
Affinity DataKd:  3.55E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570695(CHEMBL4850928)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C30H44N7O12P/c1-16(38)25(35-27(42)21(33-17(2)39)15-18-7-9-19(10-8-18)49-50(46,47)48)30(45)37-14-4-6-23(37)28(43)34-20(11-12-24(31)40)29(44)36-13-3-5-22(36)26(32)41/h7-10,16,20-23,25,38H,3-6,11-15H2,1-2H3,(H2,31,40)(H2,32,41)(H,33,39)(H,34,43)(H,35,42)(H2,46,47,48)/t16-,20+,21+,22+,23+,25+/m1/s1
Affinity DataKd:  4.34E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570696(CHEMBL4866454)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C29H41N6O13P/c1-15(36)24(33-26(41)19(31-16(2)37)13-17-7-9-18(10-8-17)48-49(45,46)47)29(44)35-12-4-6-22(35)27(42)32-20(14-23(38)39)28(43)34-11-3-5-21(34)25(30)40/h7-10,15,19-22,24,36H,3-6,11-14H2,1-2H3,(H2,30,40)(H,31,37)(H,32,42)(H,33,41)(H,38,39)(H2,45,46,47)/t15-,19+,20+,21+,22+,24+/m1/s1
Affinity DataKd:  2.29E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570692(CHEMBL4870377)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C36H55N10O14P/c1-19(47)29(35(56)46-17-5-8-27(46)33(54)42-24(13-14-28(49)50)34(55)45-16-4-7-26(45)30(37)51)44-32(53)25(18-21-9-11-22(12-10-21)60-61(57,58)59)43-31(52)23(41-20(2)48)6-3-15-40-36(38)39/h9-12,19,23-27,29,47H,3-8,13-18H2,1-2H3,(H2,37,51)(H,41,48)(H,42,54)(H,43,52)(H,44,53)(H,49,50)(H4,38,39,40)(H2,57,58,59)/t19-,23+,24+,25+,26+,27+,29+/m1/s1
Affinity DataKd:  763nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570691(CHEMBL4869894)
Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(N)=O
Show InChI InChI=1S/C49H78N15O21P/c1-23(2)17-30(56-25(4)68)42(75)58-29(13-14-36(50)69)41(74)57-28(7-5-15-54-49(52)53)40(73)59-31(18-26-9-11-27(12-10-26)85-86(82,83)84)43(76)61-34(22-66)45(78)62-33(21-65)44(77)60-32(19-38(71)72)48(81)64-16-6-8-35(64)46(79)63-39(24(3)67)47(80)55-20-37(51)70/h9-12,23-24,28-35,39,65-67H,5-8,13-22H2,1-4H3,(H2,50,69)(H2,51,70)(H,55,80)(H,56,68)(H,57,74)(H,58,75)(H,59,73)(H,60,77)(H,61,76)(H,62,78)(H,63,79)(H,71,72)(H4,52,53,54)(H2,82,83,84)/t24-,28+,29+,30+,31+,32+,33+,34+,35+,39+/m1/s1
Affinity DataKd:  8.28E+3nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570690(CHEMBL4874562)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C28H41N6O11P/c1-15(27(40)33-12-4-6-21(33)24(29)37)30-26(39)22-7-5-13-34(22)28(41)23(16(2)35)32-25(38)20(31-17(3)36)14-18-8-10-19(11-9-18)45-46(42,43)44/h8-11,15-16,20-23,35H,4-7,12-14H2,1-3H3,(H2,29,37)(H,30,39)(H,31,36)(H,32,38)(H2,42,43,44)/t15-,16+,20-,21-,22-,23-/m0/s1
Affinity DataKd:  1.85E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570689(CHEMBL4867045)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C28H41N6O13P/c1-14(25(40)32-19(10-11-22(37)38)28(43)34-12-4-5-21(34)24(29)39)30-27(42)23(15(2)35)33-26(41)20(31-16(3)36)13-17-6-8-18(9-7-17)47-48(44,45)46/h6-9,14-15,19-21,23,35H,4-5,10-13H2,1-3H3,(H2,29,39)(H,30,42)(H,31,36)(H,32,40)(H,33,41)(H,37,38)(H2,44,45,46)/t14-,15+,19-,20-,21-,23-/m0/s1
Affinity DataKd:  2.44E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570688(CHEMBL4858812)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C29H41N6O12P/c1-16(31-26(40)21(32-17(2)36)15-18-7-9-19(10-8-18)47-48(44,45)46)28(42)35-14-4-6-23(35)27(41)33-20(11-12-24(37)38)29(43)34-13-3-5-22(34)25(30)39/h7-10,16,20-23H,3-6,11-15H2,1-2H3,(H2,30,39)(H,31,40)(H,32,36)(H,33,41)(H,37,38)(H2,44,45,46)/t16-,20-,21-,22-,23-/m0/s1
Affinity DataKd:  5.71E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570686(CHEMBL4865503)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(N)=O
Show InChI InChI=1S/C25H36N5O12P/c1-13(31)21(25(38)30-11-3-4-19(30)24(37)28-17(22(26)35)9-10-20(33)34)29-23(36)18(27-14(2)32)12-15-5-7-16(8-6-15)42-43(39,40)41/h5-8,13,17-19,21,31H,3-4,9-12H2,1-2H3,(H2,26,35)(H,27,32)(H,28,37)(H,29,36)(H,33,34)(H2,39,40,41)/t13-,17+,18+,19+,21+/m1/s1
Affinity DataKd:  9.83E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570697(CHEMBL4850791)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C34H45N6O13P/c1-19(41)29(39-32(47)26(36-20(2)42)18-22-10-12-23(13-11-22)53-54(50,51)52)34(49)40-16-6-9-27(40)33(48)37-24(14-15-28(43)44)31(46)38-25(30(35)45)17-21-7-4-3-5-8-21/h3-5,7-8,10-13,19,24-27,29,41H,6,9,14-18H2,1-2H3,(H2,35,45)(H,36,42)(H,37,48)(H,38,46)(H,39,47)(H,43,44)(H2,50,51,52)/t19-,24+,25+,26+,27+,29+/m1/s1
Affinity DataKd:  3.35E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570683(CHEMBL4853735)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CNC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C32H46N7O14P/c1-17(40)27(37-29(46)22(35-25(42)16-34-18(2)41)15-19-7-9-20(10-8-19)53-54(50,51)52)32(49)39-14-4-6-24(39)30(47)36-21(11-12-26(43)44)31(48)38-13-3-5-23(38)28(33)45/h7-10,17,21-24,27,40H,3-6,11-16H2,1-2H3,(H2,33,45)(H,34,41)(H,35,42)(H,36,47)(H,37,46)(H,43,44)(H2,50,51,52)/t17-,21+,22+,23+,24+,27+/m1/s1
Affinity DataKd:  2.24E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570682(CHEMBL4846771)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C39H56N9O18P/c1-19(33(40)56)42-36(59)27-6-4-14-47(27)38(61)24(12-13-30(52)53)45-37(60)28-7-5-15-48(28)39(62)32(20(2)49)46-35(58)25(16-22-8-10-23(11-9-22)66-67(63,64)65)44-29(51)18-41-34(57)26(17-31(54)55)43-21(3)50/h8-11,19-20,24-28,32,49H,4-7,12-18H2,1-3H3,(H2,40,56)(H,41,57)(H,42,59)(H,43,50)(H,44,51)(H,45,60)(H,46,58)(H,52,53)(H,54,55)(H2,63,64,65)/t19-,20+,24-,25-,26-,27-,28-,32-/m0/s1
Affinity DataKd:  2.44E+4nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570684(CHEMBL4872230)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C30H43N6O13P/c1-16(37)25(34-27(42)21(32-17(2)38)15-18-7-9-19(10-8-18)49-50(46,47)48)30(45)36-14-4-6-23(36)28(43)33-20(11-12-24(39)40)29(44)35-13-3-5-22(35)26(31)41/h7-10,16,20-23,25,37H,3-6,11-15H2,1-2H3,(H2,31,41)(H,32,38)(H,33,43)(H,34,42)(H,39,40)(H2,46,47,48)/t16-,20+,21+,22+,23+,25+/m1/s1
Affinity DataKd:  5.55E+3nMAssay Description:Binding affinity to recombinant His-tagged Cbl-b (unknown origin) (39 to 368 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed