Compile Data Set for Download or QSAR
Found 6 of affinity data for UniProtKB/TrEMBL: P36956
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50351538(CHEMBL1824673)
Show SMILES CCCc1cc(ccn1)-c1nc(cs1)-c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C18H19N3O2S2/c1-3-4-16-11-14(9-10-19-16)18-20-17(12-24-18)13-5-7-15(8-6-13)21-25(2,22)23/h5-12,21H,3-4H2,1-2H3
Affinity DataIC50: 700nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50571643(CHEMBL4851466)
Show SMILES C[C@H](CCC(F)(F)C(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\Cn1nnnc1-c1ccccc1
Show InChI InChI=1S/C27H38F2N4O/c1-19(14-17-27(28,29)25(2,3)34)22-12-13-23-20(11-8-16-26(22,23)4)15-18-33-24(30-31-32-33)21-9-6-5-7-10-21/h5-7,9-10,15,19,22-23,34H,8,11-14,16-18H2,1-4H3/b20-15+/t19-,22-,23+,26-/m1/s1
Affinity DataIC50: 723nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50571642(CHEMBL4876668)
Show SMILES C[C@H](CCC(F)(F)C(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\Cn1nnc(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H37F3N4O/c1-18(13-16-27(29,30)25(2,3)35)22-11-12-23-19(6-5-15-26(22,23)4)14-17-34-32-24(31-33-34)20-7-9-21(28)10-8-20/h7-10,14,18,22-23,35H,5-6,11-13,15-17H2,1-4H3/b19-14+/t18-,22-,23+,26-/m1/s1
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50521013(CALCIFEDIOL | CHEBI:17933 | Calcifediol)
Show SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)CCC1=C
Show InChI InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50571644(CHEMBL4851396)
Show SMILES C[C@H](CCC(F)(F)C(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\Cn1nnnc1-c1ccc(F)cc1
Show InChI InChI=1S/C27H37F3N4O/c1-18(13-16-27(29,30)25(2,3)35)22-11-12-23-19(6-5-15-26(22,23)4)14-17-34-24(31-32-33-34)20-7-9-21(28)10-8-20/h7-10,14,18,22-23,35H,5-6,11-13,15-17H2,1-4H3/b19-14+/t18-,22-,23+,26-/m1/s1
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetSterol regulatory element-binding protein 1(Homo sapiens)
Teikyo University

Curated by ChEMBL
LigandPNGBDBM50351521(CHEMBL1824658)
Show SMILES CCc1cc(ccn1)-c1nc(cs1)-c1ccc(C)cc1
Show InChI InChI=1S/C17H16N2S/c1-3-15-10-14(8-9-18-15)17-19-16(11-20-17)13-6-4-12(2)5-7-13/h4-11H,3H2,1-2H3
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assayMore data for this Ligand-Target Pair