Compile Data Set for Download or QSAR
Found 3 of affinity data for UniProtKB/TrEMBL: O95140
TargetMitofusin-2(Homo sapiens)
The First Affiliated Hospital of Xi'an Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50581380(CHEMBL5086896)
Show SMILES O[C@H]1CC[C@@H](CC1)NC(=O)[C@H]1C[C@@H]1CCCc1ccccc1
Show InChI InChI=1S/C19H27NO2/c21-17-11-9-16(10-12-17)20-19(22)18-13-15(18)8-4-7-14-5-2-1-3-6-14/h1-3,5-6,15-18,21H,4,7-13H2,(H,20,22)/t15-,16-,17-,18-/m0/s1
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Mitofusin-2 expressed in MEF cells assessed as enhancement of mitochondrial elongation and polarization measured after 48 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetMitofusin-2(Homo sapiens)
The First Affiliated Hospital of Xi'an Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50581382(CHEMBL4639460)
Show SMILES CC1CCCCC1NC(=O)NCCCc1nnc(C2CC2)n1-c1ccccc1
Show InChI InChI=1S/C22H31N5O/c1-16-8-5-6-11-19(16)24-22(28)23-15-7-12-20-25-26-21(17-13-14-17)27(20)18-9-3-2-4-10-18/h2-4,9-10,16-17,19H,5-8,11-15H2,1H3,(H2,23,24,28)
Affinity DataEC50:  2.5nMAssay Description:Activation of human Mitofusin-2 expressed in MEF cells assessed as enhancement of mitochondrial elongation and polarization measured after 48 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetMitofusin-2(Homo sapiens)
The First Affiliated Hospital of Xi'an Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50581381(CHEMBL5088708)
Show SMILES O[C@H]1CC[C@@H](CC1)NC(=O)[C@@H]1C[C@H]1CCCc1ccccc1
Show InChI InChI=1S/C19H27NO2/c21-17-11-9-16(10-12-17)20-19(22)18-13-15(18)8-4-7-14-5-2-1-3-6-14/h1-3,5-6,15-18,21H,4,7-13H2,(H,20,22)/t15-,16-,17-,18-/m1/s1
Affinity DataEC50:  3.80nMAssay Description:Activation of human Mitofusin-2 expressed in MEF cells assessed as enhancement of mitochondrial elongation and polarization measured after 48 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid