Compile Data Set for Download or QSAR
Found 6 of affinity data for UniProtKB/TrEMBL: Q9H300
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Homo sapiens)
Oberlin College

Curated by ChEMBL
LigandPNGBDBM50572960(CHEMBL4859980)
Show SMILES O=C1CCC(=O)N1S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C16H13NO4S/c18-15-10-11-16(19)17(15)22(20,21)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2
Affinity DataIC50: 700nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
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TargetPresenilins-associated rhomboid-like protein, mitochondrial(Homo sapiens)
Oberlin College

Curated by ChEMBL
LigandPNGBDBM50572959(CHEMBL4854450)
Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N1C(=O)CCC1=O
Show InChI InChI=1S/C10H8N2O6S/c13-9-5-6-10(14)11(9)19(17,18)8-3-1-7(2-4-8)12(15)16/h1-4H,5-6H2
Affinity DataIC50: 900nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetPresenilins-associated rhomboid-like protein, mitochondrial(Homo sapiens)
Oberlin College

Curated by ChEMBL
LigandPNGBDBM50572956(CHEMBL4855230)
Show SMILES O=C1CCC(=O)N1OS(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C16H13NO5S/c18-15-10-11-16(19)17(15)22-23(20,21)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Homo sapiens)
Oberlin College

Curated by ChEMBL
LigandPNGBDBM50572955(CHEMBL4861272)
Show SMILES O=C1CCC(=O)N1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C10H9NO4S/c12-9-6-7-10(13)11(9)16(14,15)8-4-2-1-3-5-8/h1-5H,6-7H2
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Homo sapiens)
Oberlin College

Curated by ChEMBL
LigandPNGBDBM50572958(CHEMBL4856971)
Show SMILES Clc1ccccc1C(=O)OCN1C(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C15H10ClNO5S/c16-12-7-3-1-5-10(12)15(19)22-9-17-14(18)11-6-2-4-8-13(11)23(17,20)21/h1-8H,9H2
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Homo sapiens)
Oberlin College

Curated by ChEMBL
LigandPNGBDBM50572957(CHEMBL4871112)
Show SMILES O=C1CCC(=O)N1OS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C10H9NO5S/c12-9-6-7-10(13)11(9)16-17(14,15)8-4-2-1-3-5-8/h1-5H,6-7H2
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed