Compile Data Set for Download or QSAR
Found 33 of affinity data for UniProtKB/TrEMBL: Q9NS67
TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573991(CHEMBL4852965)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C19H14Cl2N2O3S/c20-13-6-11-17(18(21)12-13)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50:  457nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574021(CHEMBL4869637)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)c(Cl)c1
Show InChI InChI=1S/C16H11Cl2N3O3S2/c17-10-1-6-13(14(18)9-10)15(22)20-11-2-4-12(5-3-11)26(23,24)21-16-19-7-8-25-16/h1-9H,(H,19,21)(H,20,22)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells assessed as induction of beta-arrestin recruitment pretreated with substrate for 45 mins fo...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573993(CHEMBL4869721)
Show SMILES Clc1cccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)c1
Show InChI InChI=1S/C19H13Cl3N2O3S/c20-12-2-1-3-15(10-12)24-28(26,27)16-7-5-14(6-8-16)23-19(25)17-9-4-13(21)11-18(17)22/h1-11,24H,(H,23,25)
Affinity DataEC50:  575nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573994(CHEMBL4850296)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2Cl)c(Cl)c1
Show InChI InChI=1S/C19H13Cl3N2O3S/c20-12-5-10-15(17(22)11-12)19(25)23-13-6-8-14(9-7-13)28(26,27)24-18-4-2-1-3-16(18)21/h1-11,24H,(H,23,25)
Affinity DataEC50:  1.26E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573995(CHEMBL4873349)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)cc1
Show InChI InChI=1S/C20H16Cl2N2O3S/c1-13-2-5-16(6-3-13)24-28(26,27)17-9-7-15(8-10-17)23-20(25)18-11-4-14(21)12-19(18)22/h2-12,24H,1H3,(H,23,25)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573996(CHEMBL4866235)
Show SMILES Cc1ccccc1NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C20H16Cl2N2O3S/c1-13-4-2-3-5-19(13)24-28(26,27)16-9-7-15(8-10-16)23-20(25)17-11-6-14(21)12-18(17)22/h2-12,24H,1H3,(H,23,25)
Affinity DataEC50:  1.23E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573997(CHEMBL4846533)
Show SMILES COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)cc1
Show InChI InChI=1S/C20H16Cl2N2O4S/c1-28-16-7-3-15(4-8-16)24-29(26,27)17-9-5-14(6-10-17)23-20(25)18-11-2-13(21)12-19(18)22/h2-12,24H,1H3,(H,23,25)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573998(CHEMBL4856300)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)NCc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C20H16Cl2N2O3S/c21-15-6-11-18(19(22)12-15)20(25)24-16-7-9-17(10-8-16)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573999(CHEMBL4857734)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)NC(=O)c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C20H14Cl2N2O4S/c21-14-6-11-17(18(22)12-14)20(26)23-15-7-9-16(10-8-15)29(27,28)24-19(25)13-4-2-1-3-5-13/h1-12H,(H,23,26)(H,24,25)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM87573(2,4-Dichloro-N-[4-(pyridin-2-ylsulfamoyl)-phenyl]-...)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(Cl)c1
Show InChI InChI=1S/C18H13Cl2N3O3S/c19-12-4-9-15(16(20)11-12)18(24)22-13-5-7-14(8-6-13)27(25,26)23-17-3-1-2-10-21-17/h1-11H,(H,21,23)(H,22,24)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574000(CHEMBL4850763)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ncccn2)c(Cl)c1
Show InChI InChI=1S/C17H12Cl2N4O3S/c18-11-2-7-14(15(19)10-11)16(24)22-12-3-5-13(6-4-12)27(25,26)23-17-20-8-1-9-21-17/h1-10H,(H,22,24)(H,20,21,23)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574001(CHEMBL4852817)
Show SMILES CN(c1ccccc1)S(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C20H16Cl2N2O3S/c1-24(16-5-3-2-4-6-16)28(26,27)17-10-8-15(9-11-17)23-20(25)18-12-7-14(21)13-19(18)22/h2-13H,1H3,(H,23,25)
Affinity DataEC50:  2.57E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574002(CHEMBL4872873)
Show SMILES Clc1ccc(C(=O)Nc2cccc(c2)S(=O)(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C19H14Cl2N2O3S/c20-13-9-10-17(18(21)11-13)19(24)22-15-7-4-8-16(12-15)27(25,26)23-14-5-2-1-3-6-14/h1-12,23H,(H,22,24)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574003(CHEMBL4860134)
Show SMILES Clc1ccc(c(Cl)c1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C18H14Cl2N2O4S2/c19-13-6-11-18(17(20)12-13)28(25,26)22-15-7-9-16(10-8-15)27(23,24)21-14-4-2-1-3-5-14/h1-12,21-22H
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574004(CHEMBL4868325)
Show SMILES Clc1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C19H14Cl2N2O3S/c20-14-8-11-18(17(21)12-14)22-19(24)13-6-9-16(10-7-13)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574005(CHEMBL4847143)
Show SMILES Clc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C20H16Cl2N2O3S/c21-15-7-6-14(19(22)13-15)12-20(25)23-16-8-10-18(11-9-16)28(26,27)24-17-4-2-1-3-5-17/h1-11,13,24H,12H2,(H,23,25)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574006(CHEMBL4873007)
Show SMILES Cc1cc(Cl)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C20H17ClN2O3S/c1-14-13-15(21)7-12-19(14)20(24)22-16-8-10-18(11-9-16)27(25,26)23-17-5-3-2-4-6-17/h2-13,23H,1H3,(H,22,24)
Affinity DataEC50:  912nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574007(CHEMBL4868300)
Show SMILES Fc1cc(Cl)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C19H14ClFN2O3S/c20-13-6-11-17(18(21)12-13)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574008(CHEMBL4865504)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(Br)c1
Show InChI InChI=1S/C19H14BrClN2O3S/c20-18-12-13(21)6-11-17(18)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574009(CHEMBL4857582)
Show SMILES Cc1cc(Br)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C20H17BrN2O3S/c1-14-13-15(21)7-12-19(14)20(24)22-16-8-10-18(11-9-16)27(25,26)23-17-5-3-2-4-6-17/h2-13,23H,1H3,(H,22,24)
Affinity DataEC50:  851nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574010(CHEMBL4850346)
Show SMILES Fc1cc(Br)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C19H14BrFN2O3S/c20-13-6-11-17(18(21)12-13)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50:  479nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574011(CHEMBL4854273)
Show SMILES COc1cc(Br)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C20H17BrN2O4S/c1-27-19-13-14(21)7-12-18(19)20(24)22-15-8-10-17(11-9-15)28(25,26)23-16-5-3-2-4-6-16/h2-13,23H,1H3,(H,22,24)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574012(CHEMBL4860248)
Show SMILES Fc1cc(I)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C19H14FIN2O3S/c20-18-12-13(21)6-11-17(18)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50:  5.13E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574013(CHEMBL4861825)
Show SMILES Fc1cc(ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1)C#N
Show InChI InChI=1S/C20H14FN3O3S/c21-19-12-14(13-22)6-11-18(19)20(25)23-15-7-9-17(10-8-15)28(26,27)24-16-4-2-1-3-5-16/h1-12,24H,(H,23,25)
Affinity DataEC50:  229nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574014(CHEMBL4878026)
Show SMILES Fc1cc(ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N2O3S/c21-18-12-13(20(22,23)24)6-11-17(18)19(27)25-14-7-9-16(10-8-14)30(28,29)26-15-4-2-1-3-5-15/h1-12,26H,(H,25,27)
Affinity DataEC50:  363nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574015(CHEMBL4869253)
Show SMILES Fc1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(F)cc1Cl
Show InChI InChI=1S/C19H13ClF2N2O3S/c20-16-11-17(21)15(10-18(16)22)19(25)23-12-6-8-14(9-7-12)28(26,27)24-13-4-2-1-3-5-13/h1-11,24H,(H,23,25)
Affinity DataEC50:  141nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574016(CHEMBL4872926)
Show SMILES Clc1cnc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C18H13Cl2N3O3S/c19-12-10-16(20)17(21-11-12)18(24)22-13-6-8-15(9-7-13)27(25,26)23-14-4-2-1-3-5-14/h1-11,23H,(H,22,24)
Affinity DataEC50:  5.75E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574017(CHEMBL4868057)
Show SMILES Fc1nc(Cl)ccc1C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C18H13ClFN3O3S/c19-16-11-10-15(17(20)22-16)18(24)21-12-6-8-14(9-7-12)27(25,26)23-13-4-2-1-3-5-13/h1-11,23H,(H,21,24)
Affinity DataEC50:  2.29E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574018(CHEMBL4871933)
Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C22H16N2O5S/c25-21(19-14-15-6-4-5-9-20(15)29-22(19)26)23-16-10-12-18(13-11-16)30(27,28)24-17-7-2-1-3-8-17/h1-14,24H,(H,23,25)
Affinity DataEC50:  7.76E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574019(CHEMBL4873758)
Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1)c1ccc2ccccc2c1
Show InChI InChI=1S/C23H18N2O3S/c26-23(19-11-10-17-6-4-5-7-18(17)16-19)24-20-12-14-22(15-13-20)29(27,28)25-21-8-2-1-3-9-21/h1-16,25H,(H,24,26)
Affinity DataEC50:  8.51E+3nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50574020(CHEMBL4856118)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)C(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C20H14Cl2N2O2/c21-14-8-11-17(18(22)12-14)20(26)24-16-9-6-13(7-10-16)19(25)23-15-4-2-1-3-5-15/h1-12H,(H,23,25)(H,24,26)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573991(CHEMBL4852965)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C19H14Cl2N2O3S/c20-13-6-11-17(18(21)12-13)19(24)22-14-7-9-16(10-8-14)27(25,26)23-15-4-2-1-3-5-15/h1-12,23H,(H,22,24)
Affinity DataEC50:  912nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells assessed as induction of beta-arrestin recruitment pretreated with substrate for 45 mins fo...More data for this Ligand-Target Pair
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TargetProbable G-protein coupled receptor 27(Homo sapiens)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50573992(CHEMBL4860521)
Show SMILES Clc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)cc1
Show InChI InChI=1S/C19H13Cl3N2O3S/c20-12-1-4-15(5-2-12)24-28(26,27)16-8-6-14(7-9-16)23-19(25)17-10-3-13(21)11-18(17)22/h1-11,24H,(H,23,25)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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