Compile Data Set for Download or QSAR
Found 18 of affinity data for UniProtKB/TrEMBL: P10997
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575500(CHEMBL4866117)
Show SMILES CCCCC(=O)\C=C\c1cccc(O)c1O
Show InChI InChI=1S/C13H16O3/c1-2-3-6-11(14)9-8-10-5-4-7-12(15)13(10)16/h4-5,7-9,15-16H,2-3,6H2,1H3/b9-8+
Affinity DataIC50: 700nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575499(CHEMBL4853313)
Show SMILES CCCC(=O)\C=C\c1cccc(O)c1O
Show InChI InChI=1S/C12H14O3/c1-2-4-10(13)8-7-9-5-3-6-11(14)12(9)15/h3,5-8,14-15H,2,4H2,1H3/b8-7+
Affinity DataIC50: 800nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575498(CHEMBL4877746)
Show SMILES CCC(=O)\C=C\c1cccc(O)c1O
Show InChI InChI=1S/C11H12O3/c1-2-9(12)7-6-8-4-3-5-10(13)11(8)14/h3-7,13-14H,2H2,1H3/b7-6+
Affinity DataIC50: 800nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575497(CHEMBL439677)
Show SMILES CC(=O)\C=C\c1cccc(O)c1O
Show InChI InChI=1S/C10H10O3/c1-7(11)5-6-8-3-2-4-9(12)10(8)13/h2-6,12-13H,1H3/b6-5+
Affinity DataIC50: 800nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575509(CHEMBL4876955)
Show SMILES Oc1ccc(\C=C\C(=O)CCCCc2ccccc2O)cc1O
Show InChI InChI=1S/C19H20O4/c20-16(11-9-14-10-12-18(22)19(23)13-14)7-3-1-5-15-6-2-4-8-17(15)21/h2,4,6,8-13,21-23H,1,3,5,7H2/b11-9+
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575496(CHEMBL4867746)
Show SMILES CCCCC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C13H16O3/c1-2-3-4-11(14)7-5-10-6-8-12(15)13(16)9-10/h5-9,15-16H,2-4H2,1H3/b7-5+
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575507(CHEMBL4861462)
Show SMILES CCCC(=O)CCc1cccc(O)c1O
Show InChI InChI=1S/C12H16O3/c1-2-4-10(13)8-7-9-5-3-6-11(14)12(9)15/h3,5-6,14-15H,2,4,7-8H2,1H3
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575508(CHEMBL4861649)
Show SMILES CCCCC(=O)CCc1cccc(O)c1O
Show InChI InChI=1S/C13H18O3/c1-2-3-6-11(14)9-8-10-5-4-7-12(15)13(10)16/h4-5,7,15-16H,2-3,6,8-9H2,1H3
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575505(CHEMBL4871404)
Show SMILES CC(=O)CCc1cccc(O)c1O
Show InChI InChI=1S/C10H12O3/c1-7(11)5-6-8-3-2-4-9(12)10(8)13/h2-4,12-13H,5-6H2,1H3
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575504(CHEMBL4867456)
Show SMILES CCCCC(=O)CCc1ccc(O)c(O)c1
Show InChI InChI=1S/C13H18O3/c1-2-3-4-11(14)7-5-10-6-8-12(15)13(16)9-10/h6,8-9,15-16H,2-5,7H2,1H3
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575495(CHEMBL4862006)
Show SMILES CCCC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C12H14O3/c1-2-3-10(13)6-4-9-5-7-11(14)12(15)8-9/h4-8,14-15H,2-3H2,1H3/b6-4+
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50035607(CHEMBL75390)
Show SMILES CC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C10H10O3/c1-7(11)2-3-8-4-5-9(12)10(13)6-8/h2-6,12-13H,1H3/b3-2+
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575506(CHEMBL4876866)
Show SMILES CCC(=O)CCc1cccc(O)c1O
Show InChI InChI=1S/C11H14O3/c1-2-9(12)7-6-8-4-3-5-10(13)11(8)14/h3-5,13-14H,2,6-7H2,1H3
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575494(CHEMBL4877898)
Show SMILES CCC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H12O3/c1-2-9(12)5-3-8-4-6-10(13)11(14)7-8/h3-7,13-14H,2H2,1H3/b5-3+
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Show SMILES Oc1ccc(c(O)c1)-c1oc2cc(O)cc(O)c2c(=O)c1O
Show InChI InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575503(CHEMBL4878532)
Show SMILES CCCC(=O)CCc1ccc(O)c(O)c1
Show InChI InChI=1S/C12H16O3/c1-2-3-10(13)6-4-9-5-7-11(14)12(15)8-9/h5,7-8,14-15H,2-4,6H2,1H3
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575502(CHEMBL4856745)
Show SMILES CCC(=O)CCc1ccc(O)c(O)c1
Show InChI InChI=1S/C11H14O3/c1-2-9(12)5-3-8-4-6-10(13)11(14)7-8/h4,6-7,13-14H,2-3,5H2,1H3
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIslet amyloid polypeptide(Homo sapiens)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50575501(CHEMBL4877565)
Show SMILES CC(=O)CCc1ccc(O)c(O)c1
Show InChI InChI=1S/C10H12O3/c1-7(11)2-3-8-4-5-9(12)10(13)6-8/h4-6,12-13H,2-3H2,1H3
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregation after 24 hrs by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid