Compile Data Set for Download or QSAR
Found 2 of affinity data for UniProtKB/TrEMBL: Q9EQV9
TargetCarboxypeptidase B2(Rattus norvegicus)
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50575780(CHEMBL4878039)
Show SMILES Cn1cncc1-c1cc(F)ccc1CN1CCP(O)(=O)[C@@](CCCCN)(C1)C(O)=O
Show InChI InChI=1S/C20H28FN4O4P/c1-24-14-23-11-18(24)17-10-16(21)5-4-15(17)12-25-8-9-30(28,29)20(13-25,19(26)27)6-2-3-7-22/h4-5,10-11,14H,2-3,6-9,12-13,22H2,1H3,(H,26,27)(H,28,29)/t20-/m0/s1
Affinity DataEC50:  389nMAssay Description:Inhibition of TAFI in Sprague-Dawley rat blood TAFI incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarboxypeptidase B2(Rattus norvegicus)
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50575770(CHEMBL4858095)
Show SMILES COc1ccc(cn1)-c1ccccc1CN1CCP(O)(=O)[C@@](CCCCN)(C1)C(O)=O
Show InChI InChI=1S/C22H30N3O5P/c1-30-20-9-8-17(14-24-20)19-7-3-2-6-18(19)15-25-12-13-31(28,29)22(16-25,21(26)27)10-4-5-11-23/h2-3,6-9,14H,4-5,10-13,15-16,23H2,1H3,(H,26,27)(H,28,29)/t22-/m0/s1
Affinity DataEC50:  378nMAssay Description:Inhibition of TAFI in Sprague-Dawley rat blood TAFI incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid