Compile Data Set for Download or QSAR
Found 29 of affinity data for UniProtKB/TrEMBL: Q8C6L5
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Show SMILES Cc1nn(c(O)c1C1OC(=O)c2ccccc12)-c1nc2ccc(Cl)c(Cl)c2[nH]1
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582657(CHEMBL5082056)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CO
Show InChI InChI=1S/C17H16Cl2N4O2/c1-22-4-2-13(21-22)9-6-11(18)16(19)17-15(9)10-7-23(14(25)8-24)5-3-12(10)20-17/h2,4,6,20,24H,3,5,7-8H2,1H3
Affinity DataIC50: 440nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Show SMILES Cc1nn(c(O)c1C1OC(=O)c2ccccc12)-c1nc2ccc(Cl)c(Cl)c2[nH]1
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582653(CHEMBL5074810)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)OC(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H14Cl2F6N4O2/c1-30-4-2-12(29-30)8-6-10(20)14(21)15-13(8)9-7-31(5-3-11(9)28-15)17(32)33-16(18(22,23)24)19(25,26)27/h2,4,6,16,28H,3,5,7H2,1H3
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582697(CHEMBL5081956)
Show SMILES OCC(=O)N1CCc2[nH]c3c(Cl)c(Cl)cc(-c4cn[nH]c4)c3c2C1
Show InChI InChI=1S/C16H14Cl2N4O2/c17-11-3-9(8-4-19-20-5-8)14-10-6-22(13(24)7-23)2-1-12(10)21-16(14)15(11)18/h3-5,21,23H,1-2,6-7H2,(H,19,20)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582671(CHEMBL5094328)
Show SMILES Cc1ccc(OC(F)(F)C(=O)NCC(=O)N2CCc3[nH]c4c(Cl)c(Cl)cc(-c5ccn(C)n5)c4c3C2)cc1
Show InChI InChI=1S/C26H23Cl2F2N5O3/c1-14-3-5-15(6-4-14)38-26(29,30)25(37)31-12-21(36)35-10-8-19-17(13-35)22-16(20-7-9-34(2)33-20)11-18(27)23(28)24(22)32-19/h3-7,9,11,32H,8,10,12-13H2,1-2H3,(H,31,37)
Affinity DataIC50: 6.69E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582672(CHEMBL5086305)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CNC(=O)c1cccc(c1)-c1noc(n1)C(F)(F)F
Show InChI InChI=1S/C27H20Cl2F3N7O3/c1-38-7-5-19(36-38)15-10-17(28)22(29)23-21(15)16-12-39(8-6-18(16)34-23)20(40)11-33-25(41)14-4-2-3-13(9-14)24-35-26(42-37-24)27(30,31)32/h2-5,7,9-10,34H,6,8,11-12H2,1H3,(H,33,41)
Affinity DataIC50: 7.62E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582669(CHEMBL5092170)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CNC(=O)Cc1ccco1
Show InChI InChI=1S/C23H21Cl2N5O3/c1-29-6-4-18(28-29)14-10-16(24)22(25)23-21(14)15-12-30(7-5-17(15)27-23)20(32)11-26-19(31)9-13-3-2-8-33-13/h2-4,6,8,10,27H,5,7,9,11-12H2,1H3,(H,26,31)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582681(CHEMBL5091924)
Show SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C23H17Cl2F6N3O3/c1-11(35)37-9-18(36)34-5-4-17-21(10-34,15-2-3-16(24)19(25)20(15)32-17)33-14-7-12(22(26,27)28)6-13(8-14)23(29,30)31/h2-3,6-8,33H,4-5,9-10H2,1H3
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582691(CHEMBL5071464)
Show SMILES OCC(=O)N1CCC2Nc3c(ccc(Cl)c3Cl)C2(C1)c1c[nH]c2ccccc12
Affinity DataIC50: 8.42E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582690(CHEMBL5088714)
Show SMILES CC(=O)OCC(=O)N1CCC2Nc3c(ccc(Cl)c3Cl)C2(C1)c1c[nH]c2ccccc12
Affinity DataIC50: 8.75E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582676(CHEMBL5088840)
Show SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1ccc(cc1C=O)C(F)(F)F
Show InChI InChI=1S/C23H18Cl2F3N3O4/c1-12(33)35-10-19(34)31-7-6-18-22(11-31,15-3-4-16(24)20(25)21(15)29-18)30-17-5-2-14(23(26,27)28)8-13(17)9-32/h2-5,8-9,30H,6-7,10-11H2,1H3
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582670(CHEMBL5092651)
Show SMILES Cc1cc(CC(=O)NCC(=O)N2CCc3[nH]c4c(Cl)c(Cl)cc(-c5ccn(C)n5)c4c3C2)no1
Show InChI InChI=1S/C23H22Cl2N6O3/c1-12-7-13(29-34-12)8-19(32)26-10-20(33)31-6-4-17-15(11-31)21-14(18-3-5-30(2)28-18)9-16(24)22(25)23(21)27-17/h3,5,7,9,27H,4,6,8,10-11H2,1-2H3,(H,26,32)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582682(CHEMBL5077562)
Show SMILES OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C21H15Cl2F6N3O2/c22-14-2-1-13-18(17(14)23)30-15-3-4-32(16(34)8-33)9-19(13,15)31-12-6-10(20(24,25)26)5-11(7-12)21(27,28)29/h1-2,5-7,31,33H,3-4,8-9H2
Affinity DataIC50: 9.56E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582683(CHEMBL5089853)
Show SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)c1c[nH]c2ccccc12
Affinity DataIC50: 9.73E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582677(CHEMBL5093811)
Show SMILES OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H16Cl2F3N3O2/c21-14-6-5-13-18(17(14)22)26-15-7-8-28(16(30)9-29)10-19(13,15)27-12-3-1-11(2-4-12)20(23,24)25/h1-6,27,29H,7-10H2
Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582654(CHEMBL5078052)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CN
Show InChI InChI=1S/C17H17Cl2N5O/c1-23-4-2-13(22-23)9-6-11(18)16(19)17-15(9)10-8-24(14(25)7-20)5-3-12(10)21-17/h2,4,6,21H,3,5,7-8,20H2,1H3
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582674(CHEMBL5092231)
Show SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1cccc(Cl)c1C=O
Show InChI InChI=1S/C22H18Cl3N3O4/c1-12(30)32-10-19(31)28-8-7-18-22(11-28,14-5-6-16(24)20(25)21(14)26-18)27-17-4-2-3-15(23)13(17)9-29/h2-6,9,27H,7-8,10-11H2,1H3
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582660(CHEMBL5078495)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CNC(=O)CN
Show InChI InChI=1S/C19H20Cl2N6O2/c1-26-4-2-14(25-26)10-6-12(20)18(21)19-17(10)11-9-27(5-3-13(11)24-19)16(29)8-23-15(28)7-22/h2,4,6,24H,3,5,7-9,22H2,1H3,(H,23,28)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582684(CHEMBL5072343)
Show SMILES OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)c1c[nH]c2ccccc12
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582673(CHEMBL5094461)
Show SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1ccc(Cl)cc1C=O
Show InChI InChI=1S/C22H18Cl3N3O4/c1-12(30)32-10-19(31)28-7-6-18-22(11-28,15-3-4-16(24)20(25)21(15)26-18)27-17-5-2-14(23)8-13(17)9-29/h2-5,8-9,27H,6-7,10-11H2,1H3
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582666(CHEMBL5087235)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CNC(=O)[C@@H]1CC(F)(F)CN1
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582657(CHEMBL5082056)
Show SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CO
Show InChI InChI=1S/C17H16Cl2N4O2/c1-22-4-2-13(21-22)9-6-11(18)16(19)17-15(9)10-7-23(14(25)8-24)5-3-12(10)20-17/h2,4,6,20,24H,3,5,7-8H2,1H3
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582694(CHEMBL5091837)
Show SMILES COc1ccc(OC)c2c1NC13CN(CCC21Nc1c3ccc(Cl)c1Cl)C(=O)CO
Show InChI InChI=1S/C21H21Cl2N3O4/c1-29-13-5-6-14(30-2)19-16(13)20-7-8-26(15(28)9-27)10-21(20,25-19)11-3-4-12(22)17(23)18(11)24-20/h3-6,24-25,27H,7-10H2,1-2H3
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582655(CHEMBL5092887)
Show SMILES CNCC(=O)N1CCc2[nH]c3c(Cl)c(Cl)cc(-c4ccn(C)n4)c3c2C1
Show InChI InChI=1S/C18H19Cl2N5O/c1-21-8-15(26)25-6-4-13-11(9-25)16-10(14-3-5-24(2)23-14)7-12(19)17(20)18(16)22-13/h3,5,7,21-22H,4,6,8-9H2,1-2H3
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582686(CHEMBL5090295)
Show SMILES OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)c1c[nH]c2cc(Cl)ccc12
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582680(CHEMBL5076890)
Show SMILES COc1ccccc1NC12CN(CCC1=Nc1c2ccc(Cl)c1Cl)C(=O)CO
Show InChI InChI=1S/C20H19Cl2N3O3/c1-28-15-5-3-2-4-14(15)24-20-11-25(17(27)10-26)9-8-16(20)23-19-12(20)6-7-13(21)18(19)22/h2-7,24,26H,8-11H2,1H3
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582698(CHEMBL4448176)
Show SMILES Nc1ccc(cn1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CO
Show InChI InChI=1S/C18H16Cl2N4O2/c19-12-5-10(9-1-2-14(21)22-6-9)16-11-7-24(15(26)8-25)4-3-13(11)23-18(16)17(12)20/h1-2,5-6,23,25H,3-4,7-8H2,(H2,21,22)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute of Materia Medica (SIMM)

Curated by ChEMBL
LigandPNGBDBM50582693(CHEMBL5080586)
Show SMILES OCC(=O)N1C[C@H]2[C@H]3O[C@]4(Nc5ccc(Cl)cc35)c3ccc(Cl)c(Cl)c3N[C@]24C1
Show InChI InChI=1S/C20H16Cl3N3O3/c21-9-1-4-14-10(5-9)18-12-6-26(15(28)7-27)8-19(12)20(24-14,29-18)11-2-3-13(22)16(23)17(11)25-19/h1-5,12,18,24-25,27H,6-8H2/t12-,18-,19+,20+/m0/s1
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid