Compile Data Set for Download or QSAR
Found 6 of affinity data for UniProtKB/TrEMBL: Q9Z0K8
TargetPantetheinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM480917(7-oxa-2-azaspiro[3.5]non-2-yl(2-{[2-(pyrazin-2-yl)...)
Show SMILES CC(C)(Nc1ncc(cn1)C(=O)N1CC2(C1)CCOCC2)c1cnccn1
Show InChI InChI=1S/C19H24N6O2/c1-18(2,15-11-20-5-6-21-15)24-17-22-9-14(10-23-17)16(26)25-12-19(13-25)3-7-27-8-4-19/h5-6,9-11H,3-4,7-8,12-13H2,1-2H3,(H,22,23,24)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPantetheinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM480931(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[(1S)-1-(pyrazin-...)
Show SMILES C[C@H](Nc1ncc(cn1)C(=O)N1CCC2(C1)CCOCC2)c1cnccn1
Show InChI InChI=1S/C19H24N6O2/c1-14(16-12-20-5-6-21-16)24-18-22-10-15(11-23-18)17(26)25-7-2-19(13-25)3-8-27-9-4-19/h5-6,10-12,14H,2-4,7-9,13H2,1H3,(H,22,23,24)/t14-/m0/s1
Affinity DataIC50: 0.560nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantetheinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM394644(3-[(2-{[1-(pyrimidin-5-yl)cyclopropyl]amino}pyrimi...)
Show SMILES O=C(c1cnc(NC2(CC2)c2cncnc2)nc1)c1cccc(c1)C#N
Show InChI InChI=1S/C19H14N6O/c20-7-13-2-1-3-14(6-13)17(26)15-8-23-18(24-9-15)25-19(4-5-19)16-10-21-12-22-11-16/h1-3,6,8-12H,4-5H2,(H,23,24,25)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPantetheinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM480973(US10906888, Example 190)
Show SMILES O=C(N1CCCCC1)c1cnc(NC2(CC2)c2cncnc2)nc1
Show InChI InChI=1S/C17H20N6O/c24-15(23-6-2-1-3-7-23)13-8-20-16(21-9-13)22-17(4-5-17)14-10-18-12-19-11-14/h8-12H,1-7H2,(H,20,21,22)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetPantetheinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Show SMILES O=C(N1CCC2(C1)CCOCC2)c1cnc(NCc2cnccn2)nc1
Show InChI InChI=1S/C18H22N6O2/c25-16(24-6-1-18(13-24)2-7-26-8-3-18)14-9-21-17(22-10-14)23-12-15-11-19-4-5-20-15/h4-5,9-11H,1-3,6-8,12-13H2,(H,21,22,23)
Affinity DataIC50: 25nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
TargetPantetheinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Show SMILES O=C(N1CCC2(C1)CCOCC2)c1cnc(NCc2cnccn2)nc1
Show InChI InChI=1S/C18H22N6O2/c25-16(24-6-1-18(13-24)2-7-26-8-3-18)14-9-21-17(22-10-14)23-12-15-11-19-4-5-20-15/h4-5,9-11H,1-3,6-8,12-13H2,(H,21,22,23)
Affinity DataIC50: 53nMAssay Description:Inhibition of mouse plasma vanin-1More data for this Ligand-Target Pair