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Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50058283(6-(4-Benzyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1...)
Affinity DataIC50:  0.000813nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408165(CHEMBL299231)
Affinity DataIC50:  0.00398nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408166(CHEMBL416662)
Affinity DataIC50:  0.0813nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408162(CHEMBL299634)
Affinity DataIC50:  0.288nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408167(CHEMBL53416)
Affinity DataIC50:  0.355nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)
Affinity DataIC50:  0.447nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408168(CHEMBL49932)
Affinity DataIC50:  0.794nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataIC50:  0.880nMAssay Description:Antagonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced response after 45 mins...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407784(CHEMBL51118)
Affinity DataIC50:  0.912nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50081975(6-(4-Methyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1...)
Affinity DataIC50:  0.977nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407789(CHEMBL52772)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407786(CHEMBL54720)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408171(CHEMBL53490)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408155(CHEMBL54125)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408164(CHEMBL52625)
Affinity DataIC50:  2.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408152(CHEMBL53662)
Affinity DataIC50:  6.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50407769(CHEMBL301765)
Affinity DataIC50:  12nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408159(CHEMBL300692)
Affinity DataIC50:  13nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408174(CHEMBL300725)
Affinity DataIC50:  14nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Affinity DataIC50:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408157(CHEMBL432897)
Affinity DataIC50:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408170(CHEMBL299097)
Affinity DataIC50:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408163(CHEMBL52867)
Affinity DataIC50:  28nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408154(CHEMBL50740)
Affinity DataIC50:  31nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408173(CHEMBL52612)
Affinity DataIC50:  46nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408169(CHEMBL53195)
Affinity DataIC50:  87nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408156(CHEMBL52800)
Affinity DataIC50:  117nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50459885(CHEMBL1382868)
Affinity DataIC50:  430nMAssay Description:Inhibition of human 5-HT3AB receptor expressed in transient A201 cells after 30 mins by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50174702((R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50150673(CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]- GR-65630 binding to rabbit ileum muscularis 5-HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408158(CHEMBL50456)
Affinity DataIC50:  1.29E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)
Affinity DataIC50:  1.32E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408151(CHEMBL299524)
Affinity DataIC50:  2.57E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408161(CHEMBL54246)
Affinity DataIC50:  3.02E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding activity against 5-hydroxytryptamine 1A receptor from human brain cortex using [3H]8-OH-DPAT-HT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding activity radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408172(CHEMBL51225)
Affinity DataIC50:  2.75E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408160(CHEMBL52007)
Affinity DataIC50:  2.82E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408153(CHEMBL51675)
Affinity DataIC50:  3.72E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408150(CHEMBL415933)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408176(CHEMBL298649)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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