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Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50601574(CHEMBL5201074)
Affinity DataKd:  0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50568740(CHEMBL4860528)
Affinity DataKd:  0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50601567(CHEMBL5206565)
Affinity DataKd:  0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataKd:  0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKd:  0.316nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50035513(CHEMBL286607 | CHEMBL1775000 | 4-Fluoro-N-{2-[4-(2...)
Affinity DataKd:  0.340nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 1 receptor using rabbit jugular vein assay in the absence of endotheliumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKd:  3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50423462(CHEMBL251835)
Affinity DataKd:  28nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50224302(CHEMBL31783)
Affinity DataKd:  43nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50423465(ERGOLINE)
Affinity DataKd:  50nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50034355((3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Affinity DataKd:  50.1nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKd:  501nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd:  794nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in pig frontal cortex membranes using [8H]-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50224305(CHEMBL285355)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
LigandPNGBDBM50224303(CHEMBL283686)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in pig frontal cortex membranes using [8H]-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKd:  3.00E+4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed