Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 366 of ec50 for UniProtKB: P41231
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195835(({[({[(2R,3S,4R,5R)-5-[7-fluoro-6-(methylsulfanyl)...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50197695(({[({[(2R,3S,4R,5R)-5-(5-fluoro-1,3-benzothiazol-2...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195845(({[({[(2R,3S,4R,5R)-5-[6-(dimethylamino)-7-fluoro-...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195825(({[({[(2R,3S,4R,5R)-5-(7-fluoro-1-oxo-1,2-dihydroi...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195825(({[({[(2R,3S,4R,5R)-5-(7-fluoro-1-oxo-1,2-dihydroi...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at wild type P2Y2 receptor (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195847(({[({[(2R,3S,4R,5R)-5-(7-fluoro-6-methoxy-1-oxo-1,...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50197694(({[({[(2R,3S,4R,5R)-5-(6-chloro-4-fluoro-1,3-benzo...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50197698(({[({[(2R,3S,4R,5R)-5-(6-chloro-1,3-benzothiazol-2...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50205406(((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human P2Y2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50205406(((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50205406(((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50205406(((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50197696(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(trifluorom...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195828(({[({[(2R,3S,4R,5R)-5-(7-chloro-1-oxo-1,2-dihydroi...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195842(({[({[(2R,3S,4R,5R)-5-(7-cyano-1-oxo-1,2-dihydrois...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195840(({[({[(2R,3S,4R,5R)-5-(6,7-dichloro-1-oxo-1,2-dihy...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50306712(((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidi...)
Affinity DataEC50:  15.9nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 2 (hP2Y2) stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50306712(((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidi...)
Affinity DataEC50:  15.9nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 2 (hP2Y2) stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50306712(((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidi...)
Affinity DataEC50:  15.9nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50319144(((1S,2S,4S,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195822(({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihy...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of PLC-induced [3H]inositol phosphate production afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50197697(({[({[(2R,3S,4R,5R)-5-(1,3-benzothiazol-2-yl)-3,4-...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50341880(((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-thioxo-3,4...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195830(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(7-methoxy-1-o...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50496860(CHEMBL1198849)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells using [3H]inositol as substrate assessed as [3H]inositol phosphat...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50319143(CHEMBL1083764 | CHEMBL1198849 | N4-Methoxycytidine...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50270550(CHEMBL503798 | {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  30nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195834(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-{4-oxo-4H,5H-t...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195826(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(1-oxo-1,2-dih...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50371572(CHEMBL406266)
Affinity DataEC50:  34nMAssay Description:Agonist activity at P2Y2 receptor expressed in human 1321 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195833(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-oxo-5,6-dih...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50195844(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-methyl-1-ox...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50199176(2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-di...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50199176(2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-di...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50199176(2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-di...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50197693(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-methoxy-1,3...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as IP accumulation by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50371610(CHEMBL1162198)
Affinity DataEC50:  44nMAssay Description:Agonist activity at P2Y2 receptor expressed in human 1321 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50012978(CHEMBL3261369)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50012978(CHEMBL3261369)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of [3H]inositol phosphate accumulation by liquid scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50199176(2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-di...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as IP accumulation by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50319143(CHEMBL1083764 | CHEMBL1198849 | N4-Methoxycytidine...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Ucb-Group

Curated by ChEMBL
LigandPNGBDBM50371598(CHEMBL1162170)
Affinity DataEC50:  52nMAssay Description:Agonist activity at P2Y2 receptor expressed in human 1321 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 366 total ) | Next | Last >>
Jump to: