Compile Data Set for Download or QSAR
Found 3 of ec50 for UniProtKB: P28647
TargetAdenosine receptor A3(Rattus norvegicus)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50550814(CHEMBL4747947)
Show SMILES Clc1ccc(cc1)-n1c(nc2ccccc2c1=O)-c1sc(NC(=O)c2ccco2)nc1-c1ccccc1
Show InChI InChI=1S/C28H17ClN4O3S/c29-18-12-14-19(15-13-18)33-25(30-21-10-5-4-9-20(21)27(33)35)24-23(17-7-2-1-3-8-17)31-28(37-24)32-26(34)22-11-6-16-36-22/h1-16H,(H,31,32,34)
Affinity DataEC50:  5.30nMAssay Description:Antagonist activity at rat A3AR expressed in CHO cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulation inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAdenosine receptor A3(Rattus norvegicus)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50550814(CHEMBL4747947)
Show SMILES Clc1ccc(cc1)-n1c(nc2ccccc2c1=O)-c1sc(NC(=O)c2ccco2)nc1-c1ccccc1
Show InChI InChI=1S/C28H17ClN4O3S/c29-18-12-14-19(15-13-18)33-25(30-21-10-5-4-9-20(21)27(33)35)24-23(17-7-2-1-3-8-17)31-28(37-24)32-26(34)22-11-6-16-36-22/h1-16H,(H,31,32,34)
Affinity DataEC50:  57nMAssay Description:Antagonist activity at rat A3AR expressed in CHO cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulation at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAdenosine receptor A3(Rattus norvegicus)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50550814(CHEMBL4747947)
Show SMILES Clc1ccc(cc1)-n1c(nc2ccccc2c1=O)-c1sc(NC(=O)c2ccco2)nc1-c1ccccc1
Show InChI InChI=1S/C28H17ClN4O3S/c29-18-12-14-19(15-13-18)33-25(30-21-10-5-4-9-20(21)27(33)35)24-23(17-7-2-1-3-8-17)31-28(37-24)32-26(34)22-11-6-16-36-22/h1-16H,(H,31,32,34)
Affinity DataEC50:  1.72E+3nMAssay Description:Antagonist activity at rat A3AR expressed in CHO cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulation at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid