Compile Data Set for Download or QSAR
Found 6 of ic50 for UniProtKB: P28647
TargetAdenosine receptor A1/A2a/A2b/A3(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50009552(2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCCC3)ncnc12
Show InChI InChI=1S/C16H23N5O4/c22-6-10-12(23)13(24)16(25-10)21-8-19-11-14(17-7-18-15(11)21)20-9-4-2-1-3-5-9/h7-10,12-13,16,22-24H,1-6H2,(H,17,18,20)/t10-,12-,13-,16-/m1/s1
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1/A2a/A2b/A3(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50118810((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...)
Show SMILES C[C@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)/t11-,13-,15-,16-,19-/m1/s1
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1/A2a/A2b/A3(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50224560(CHEMBL605654)
Show SMILES CCCNc1ncnc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C13H19N5O4/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(21)9(20)7(4-19)22-13/h5-7,9-10,13,19-21H,2-4H2,1H3,(H,14,15,16)/t7-,9-,10-,13?/m1/s1
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1/A2a/A2b/A3(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50118810((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...)
Show SMILES C[C@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)/t11-,13-,15-,16-,19-/m1/s1
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1/A2a/A2b/A3(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50224562(CHEMBL605067)
Show SMILES OC[C@H]1OC([C@H](O)[C@@H]1O)n1ncc2c(NC3CCCCC3)ncnc12
Show InChI InChI=1S/C16H23N5O4/c22-7-11-12(23)13(24)16(25-11)21-15-10(6-19-21)14(17-8-18-15)20-9-4-2-1-3-5-9/h6,8-9,11-13,16,22-24H,1-5,7H2,(H,17,18,20)/t11-,12-,13-,16?/m1/s1
Affinity DataIC50: 2.02E+4nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1/A2a/A2b/A3(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50224561(CHEMBL605655)
Show SMILES CCCNc1ncnc2n(ncc12)C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C13H19N5O4/c1-2-3-14-11-7-4-17-18(12(7)16-6-15-11)13-10(21)9(20)8(5-19)22-13/h4,6,8-10,13,19-21H,2-3,5H2,1H3,(H,14,15,16)/t8-,9-,10-,13?/m1/s1
Affinity DataIC50: 7.65E+4nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair