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Found 11 of ic50 data for polymerid = 50004060
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259583(3-amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyra...)
Affinity DataIC50:  950nMAssay Description:Inhibition of rat ASIC3 assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157090(6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of ASIC3 in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074922((+-)-2-fluoro-alpha-methyl-4-biphenylacetic acid |...)
Affinity DataIC50:  2.29E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50250133(Butibufen)
Affinity DataIC50:  2.88E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50250130(CHEMBL4083814)
Affinity DataIC50:  3.02E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  3.09E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)
Affinity DataIC50:  3.89E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295285((4-Isobutyl-phenyl)-acetic acid | 2-(4-isobutylphe...)
Affinity DataIC50:  4.17E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  5.13E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50250131(CHEMBL190275)
Affinity DataIC50:  7.08E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50250132(CHEMBL4080879)
Affinity DataIC50:  8.91E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed