Compile Data Set for Download or QSAR
Found 3 of kd for UniProtKB: Q8TF76
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50567047(CHEMBL4848254)
Show SMILES CN(C)c1nccc(n1)-c1cnn2ncccc12
Show InChI InChI=1S/C12H12N6/c1-17(2)12-13-7-5-10(16-12)9-8-15-18-11(9)4-3-6-14-18/h3-8H,1-2H3
Affinity DataKd:  15nMAssay Description:Binding affinity to wild-type human partial length HASPIN (I452 to K798 residues) expressed in mammalian expression system measured after 1 hr by com...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50248614(CHEMBL4066819)
Show SMILES COCCNC(=O)c1ccc(Oc2sc(C(N)=O)c3CCc4cnsc4-c23)cn1
Show InChI InChI=1S/C19H18N4O4S2/c1-26-7-6-21-18(25)13-5-3-11(9-22-13)27-19-14-12(16(28-19)17(20)24)4-2-10-8-23-29-15(10)14/h3,5,8-9H,2,4,6-7H2,1H3,(H2,20,24)(H,21,25)
Affinity DataKd:  86nMAssay Description:Binding affinity to partial length wild-type human HASPIN (I452 to K798 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50560888(CHEMBL4749646)
Show SMILES CC(C)c1ccn2ncnc(N[C@H]3CC[C@H](CC3)N3CCN(CC3)C(=O)CCC(=O)N3CCC(CCN4CCN(CC4)c4ccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c5c4)CC3)c12
Show InChI InChI=1S/C47H63N11O6/c1-31(2)36-16-20-57-43(36)44(48-30-49-57)50-33-3-5-34(6-4-33)53-25-27-56(28-26-53)42(61)12-11-41(60)55-18-14-32(15-19-55)13-17-52-21-23-54(24-22-52)35-7-8-37-38(29-35)47(64)58(46(37)63)39-9-10-40(59)51-45(39)62/h7-8,16,20,29-34,39H,3-6,9-15,17-19,21-28H2,1-2H3,(H,48,49,50)(H,51,59,62)/t33-,34+,39?
Affinity DataKd:  780nMAssay Description:Displacement of polymer supported probe 25 binding to GSG2 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by p...More data for this Ligand-Target Pair