Compile Data Set for Download or QSAR
Report error Found 306 of ic50 for UniProtKB: Q16236
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human Keap1 KELCH domain (321 to 609 residues) expressed in Escherichia coli BL21 DE3 pLysS cells/Nrf2 (unknown origin) protein-protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568484BDBM50568484(CHEMBL4865999)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568478BDBM50568478(CHEMBL4860663 | US12122742, Compound I-d-3)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321036BDBM50321036(CHEMBL4160447)
Affinity DataIC50: 10nMAssay Description:Inhibition of Keap1 kelch domain (unknow origin)/Nrf2-ETGE peptide (unknown origin) interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321027BDBM50321027(CHEMBL4175603)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length Flag/His-tagged Keap1 kelch domain (unknown origin)/full length Avi-tagged Nrf2 (unknown origin) interaction after 2.25 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321036BDBM50321036(CHEMBL4160447)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length Flag/His-tagged Keap1 kelch domain (unknown origin)/full length Avi-tagged Nrf2 (unknown origin) interaction after 2.25 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568482BDBM50568482(CHEMBL4858288)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568475BDBM50568475(CHEMBL4846463)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109368BDBM50109368(CHEMBL3601212)
Affinity DataIC50: 13nMAssay Description:Inhibition of Keap1 Kelch domain/FITC-9mer Nrf2 (unknown origin) interaction after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109368BDBM50109368(CHEMBL3601212)
Affinity DataIC50: 14nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535176BDBM50535176(CHEMBL4544116)
Affinity DataIC50: 16nMAssay Description:Inhibition of Keap1 Kelch domain/FITC-9mer Nrf2 (unknown origin) interaction after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109404BDBM50109404(CHEMBL3601208)
Affinity DataIC50: 18nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640677BDBM50640677(CHEMBL5571025)
Affinity DataIC50: 19nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200461BDBM50200461(CHEMBL3946369)
Affinity DataIC50: 22nMAssay Description:Inhibition of Keap1/Nrf2 (unknown origin) interaction assessed as displacement of FITC-betaAla-DEETGEF-OH from Keap1 Kelch domain after 1 hr by FITC-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649618BDBM50649618(Halofuginone | Halofuginona | Halofuginon | Ht-100...)
Affinity DataIC50: 22nMAssay Description:Inhibition of NRF2 in human KYSE-70 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640676BDBM50640676(CHEMBL5570595)
Affinity DataIC50: 22nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 25nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640392BDBM50640392(CHEMBL5556774)
Affinity DataIC50: 26nMAssay Description:Inhibition of human Keap1 KELCH domain (321 to 609 residues) expressed in Escherichia coli BL21 DE3 pLysS cells/Nrf2 (unknown origin) protein-protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 29nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 29nMAssay Description:Inhibition of Keap1/Nrf2 complex (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535743BDBM50535743(CHEMBL459546 | CHEBI:3197)
Affinity DataIC50: 29nMAssay Description:Inhibition of NRF2 in human MDA-MB-231 cells harboring ARE-GFP-Luc assessed as reduction in ARE-luciferase activity after 16 hrs by firefly luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 31nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568477BDBM50568477(CHEMBL4853900 | US12122742, Compound I-d-1)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109371BDBM50109371(CHEMBL3601215)
Affinity DataIC50: 34nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109367BDBM50109367(CHEMBL3601211)
Affinity DataIC50: 37nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649618BDBM50649618(Halofuginone | Halofuginona | Halofuginon | Ht-100...)
Affinity DataIC50: 37nMAssay Description:Inhibition of NRF2 in human A549 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109366BDBM50109366(CHEMBL3601210)
Affinity DataIC50: 42nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109396BDBM50109396(CHEMBL3601221)
Affinity DataIC50: 42nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50638992BDBM50638992(CHEMBL5563991)
Affinity DataIC50: 45nMAssay Description:Inhibition of His-tagged human Keap1 Kelch domain /FITC-labelled-9mer Nrf2 (unknown origin) protein-protein interaction incubated for 1 hr by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109392BDBM50109392(CHEMBL3601217)
Affinity DataIC50: 47nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109369BDBM50109369(CHEMBL3601213)
Affinity DataIC50: 50nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639001BDBM50639001(CHEMBL5561002)
Affinity DataIC50: 50nMAssay Description:Inhibition of His-tagged human Keap1 Kelch domain /FITC-labelled-9mer Nrf2 (unknown origin) protein-protein interaction incubated for 1 hr by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109365BDBM50109365(CHEMBL3601209)
Affinity DataIC50: 54nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640670BDBM50640670(CHEMBL5595521)
Affinity DataIC50: 54nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50537622BDBM50537622(CHEMBL4634168)
Affinity DataIC50: 55nMAssay Description:Inhibition of Keap1-Nrf2 Interaction (unknown origin) by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561983BDBM561983(US11396496, Compound A1 | BDBM50369389)
Affinity DataIC50: 60nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130549BDBM50130549(CHEMBL3632711)
Affinity DataIC50: 63nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 63nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561983BDBM561983(US11396496, Compound A1 | BDBM50369389)
Affinity DataIC50: 63nMAssay Description:Inhibition of Keap1-Nrf2 Interaction (unknown origin) by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109394BDBM50109394(CHEMBL3601219)
Affinity DataIC50: 66nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640676BDBM50640676(CHEMBL5570595)
Affinity DataIC50: 69nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640672BDBM50640672(CHEMBL5567314)
Affinity DataIC50: 72nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561992BDBM561992(US11396496, Compound B0 | BDBM50537618)
Affinity DataIC50: 73nMAssay Description:Inhibition of Keap1-Nrf2 Interaction (unknown origin) by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 415702BDBM415702(US10442759, Compound I-14)
Affinity DataIC50: 75nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639000BDBM50639000(CHEMBL5558711)
Affinity DataIC50: 78nMAssay Description:Inhibition of His-tagged human Keap1 Kelch domain /FITC-labelled-9mer Nrf2 (unknown origin) protein-protein interaction incubated for 1 hr by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568475BDBM50568475(CHEMBL4846463)
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640677BDBM50640677(CHEMBL5571025)
Affinity DataIC50: 89nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639002BDBM50639002(CHEMBL5562900)
Affinity DataIC50: 91nMAssay Description:Inhibition of His-tagged human Keap1 Kelch domain /FITC-labelled-9mer Nrf2 (unknown origin) protein-protein interaction incubated for 1 hr by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Hangzhou City University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640678BDBM50640678(CHEMBL5556087)
Affinity DataIC50: 92nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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