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TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 7nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569442(CHEMBL4864480)
Affinity DataIC50: 60nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 60nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512726(CHEMBL4459950)
Affinity DataIC50: 84nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512718(CHEMBL4524932)
Affinity DataIC50: 191nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512717(CHEMBL4435689)
Affinity DataIC50: 203nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512715(CHEMBL4443717)
Affinity DataIC50: 339nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569444(CHEMBL4848472)
Affinity DataIC50: 340nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 550nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512716(CHEMBL4439662)
Affinity DataIC50: 584nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197518(CHEMBL3747171)
Affinity DataIC50: 690nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM314833( (−) (R) 3-[3-({[4-(5-Chloropyridin-3-yl)phe...)
Affinity DataIC50: 765nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197520(CHEMBL3921251)
Affinity DataIC50: 790nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM314837((R/S) 3-[3- ({Cyclopentyl[4-(5- methylpyridin-3-yl...)
Affinity DataIC50: 818nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50453466(CHEMBL4218509)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512724(CHEMBL4456039)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50207323(CHEMBL3897959)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197516(CHEMBL3961576)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50453468(CHEMBL4205849)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50512725(CHEMBL4537349)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50453467(CHEMBL4210116)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50453469(CHEMBL4213574)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of mPGES1 in mouse 3T3L1 cells assessed as reduction in PGE2 production after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed