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Found 38 of ki for UniProtKB: P17538
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024092(6-Iodomethylene-4-phenyl-tetrahydro-pyran-2-one | ...)
Affinity DataKi:  5.30nMAssay Description:Binding constant of the compound alpha-chymotrypsin was determined by competitive inhibition assay with BTEE as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50014743(CHEMBL132171 | N-(1-{2-[2-(1-Benzyl-3,3,3-trifluor...)
Affinity DataKi:  17nMAssay Description:Binding affinity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50014731(3-[(1-{2-[2-(3-Methoxycarbonyl-propionylamino)-pro...)
Affinity DataKi:  79nMAssay Description:Binding affinity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025866(CHEMBL60695 | N-[1R-(2-phenyl ethyl)]benzamide dif...)
Affinity DataKi:  270nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025877(CHEMBL58683 | N-[1R-(2-phenyl ethyl)]propanamide d...)
Affinity DataKi:  290nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataKi:  320nMAssay Description:Inhibitory activity against human ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025875(2-Amino-N-[1R-(2-phenyl ethyl)]propanamide boronic...)
Affinity DataKi:  320nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025872(CHEMBL293513 | N-[1R-(2-phenyl ethyl)]benzamide bo...)
Affinity DataKi:  360nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521743(US11149067, Compound Ahp2)
Affinity DataKi:  370nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025870(CHEMBL57262 | N-(2-phenyl ethyl)benzamide difluoro...)
Affinity DataKi:  650nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025860(CHEMBL292664 | N-(2-phenyl ethyl)benzamide boronic...)
Affinity DataKi:  650nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025868(2-Amino-N-(2-phenyl ethyl)propanamide difluorobora...)
Affinity DataKi:  1.40E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025865(CHEMBL292593 | N-[1R-(2-phenyl ethyl)]acetamide di...)
Affinity DataKi:  1.70E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025874(2-Amino-N-benzylpropanamide difluoroborane | CHEMB...)
Affinity DataKi:  2.00E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521750(US11149067, Compound Ahp9)
Affinity DataKi:  2.10E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025862(CHEMBL58706 | N-[1R-(2-phenyl ethyl)]acetamide bor...)
Affinity DataKi:  2.10E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition constant against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025861(CHEMBL56829 | N-benzylbenzamide difluoroborane)
Affinity DataKi:  5.00E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025859(CHEMBL61146 | N-(2-phenyl ethyl)acetamide boronic ...)
Affinity DataKi:  6.50E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025863(2-Amino-N-[(1R)-benzyl]propanamide difluoroborane ...)
Affinity DataKi:  6.50E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025871(CHEMBL430767 | N-(2-phenyl ethyl)acetamide difluor...)
Affinity DataKi:  7.40E+3nMAssay Description:Competetive inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50126635(3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5...)
Affinity DataKi: >2.20E+4nMAssay Description:In vitro inhibitory activity of the compound was tested against serine protease ChymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287589((S)-3-Acetylamino-2,2-difluoro-4-phenyl-butyric ac...)
Affinity DataKi:  3.40E+4nMpH: 7.8Assay Description:Reversible inhibitory activity of the compound toward alpha-chymotrypsin (5 nM concentration) at a pH of 7.8 by progress curve method.More data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521751(US11149067, Compound Ahp10)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521749(US11149067, Compound Ahp8)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521747(US11149067, Compound Ahp6)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521746(US11149067, Compound Ahp5)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521745(US11149067, Compound Ahp4)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521744(US11149067, Compound Ahp3)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM521742(US11149067, Compound Ahp1)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024093(6-Iodomethylene-5-phenyl-tetrahydro-pyran-2-one | ...)
Affinity DataKi:  5.50E+4nMAssay Description:Binding constant of the compound alpha-chymotrypsin was determined by competitive inhibition assay with Suc-Ala-Ala-Pro-Phe-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076819(4-((S)-1-Hydroxymethyl-2-phenyl-ethylamino)-pyridi...)
Affinity DataKi:  1.15E+5nMAssay Description:Binding affinity of the compound was evaluated against against human chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287590(CHEMBL291936 | N-((S)-1-Benzyl-2,2-difluoro-but-3-...)
Affinity DataKi:  4.60E+5nMpH: 7.8Assay Description:Reversible inhibitory activity of the compound toward alpha-chymotrypsin (5 nM concentration) at a pH of 7.8 by progress curve method.More data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288336(1-Benzoyl-pyrrolidine-2-carboxylic acid ((S)-1-(R)...)
Affinity DataKi:  8.20E+5nMAssay Description:Compound was tested for inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284351(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ter...)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition constant of the compound against Alpha-chymotrypsin inhibitor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287591((S)-3-Acetylamino-2-fluoro-4-phenyl-butyric acid m...)
Affinity DataKi:  6.44E+6nMpH: 7.8Assay Description:Reversible inhibitory activity of the compound toward alpha-chymotrypsin (5 nM concentration) at a pH of 7.8 by progress curve method.More data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287591((S)-3-Acetylamino-2-fluoro-4-phenyl-butyric acid m...)
Affinity DataKi:  6.44E+6nMpH: 7.8Assay Description:Reversible inhibitory activity of the compound toward alpha-chymotrypsin (5 nM concentration) at a pH of 7.8 by progress curve method.More data for this Ligand-Target Pair
In DepthDetails Article