Compile Data Set for Download or QSAR
Report error Found 1244 of ki for UniProtKB: P08246
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039635BDBM50039635(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.00700nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039646BDBM50039646(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.00800nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036480BDBM50036480(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.00800nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039637BDBM50039637(2,6-Dichloro-3-[(2-dimethylamino-ethyl)-methyl-sul...)
Affinity DataKi:  0.0100nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036478BDBM50036478(3-Carboxymethoxy-2,6-dichloro-benzoic acid 4-isopr...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036476BDBM50036476(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036477BDBM50036477(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0130nMAssay Description:Binding affinity against Elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029704BDBM50029704(2-(4-Benzyl-5-oxo-2,5-dihydro-furan-3-yloxymethyl)...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036481BDBM50036481(2,6-Dichloro-3-[(2-dimethylamino-ethyl)-methyl-sul...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036477BDBM50036477(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036475BDBM50036475(2,6-Dichloro-3-(2-pyrrolidin-1-yl-ethoxy)-benzoic ...)
Affinity DataKi:  0.0140nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118030BDBM50118030(4-(5-Cyclopropylaminomethyl-pyrazine-2-carbonyl)-3...)
Affinity DataKi:  0.0140nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029709BDBM50029709(2-(4-Benzyl-2-methyl-5-oxo-2,5-dihydro-furan-3-ylo...)
Affinity DataKi:  0.0160nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029710BDBM50029710(4-Isopropyl-6-methoxy-2-(2-methyl-5-oxo-4-phenyl-2...)
Affinity DataKi:  0.0210nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285289BDBM50285289(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0220nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029699BDBM50029699(2,6-Dichloro-benzoic acid 4-isopropyl-6-methoxy-1,...)
Affinity DataKi:  0.0230nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029699BDBM50029699(2,6-Dichloro-benzoic acid 4-isopropyl-6-methoxy-1,...)
Affinity DataKi:  0.0230nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095523BDBM50095523([(S)-2-methyl-1-((S)-2-{(S)-2-methyl-1-[5-(3-methy...)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095523BDBM50095523([(S)-2-methyl-1-((S)-2-{(S)-2-methyl-1-[5-(3-methy...)
Affinity DataKi:  0.0250nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095523BDBM50095523([(S)-2-methyl-1-((S)-2-{(S)-2-methyl-1-[5-(3-methy...)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095523BDBM50095523([(S)-2-methyl-1-((S)-2-{(S)-2-methyl-1-[5-(3-methy...)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of human neutrophil elastase HNE, hydrolysis of MeO-Suc-Ala-Ala-Pro-Val-pNaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029717BDBM50029717(2-(3-Chloro-6-methyl-2-oxo-2H-pyran-4-yloxymethyl)...)
Affinity DataKi:  0.0250nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029698BDBM50029698(4-Isopropyl-6-methoxy-1,1-dioxo-2-(5-oxo-4-phenyl-...)
Affinity DataKi:  0.0250nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029696BDBM50029696(2-(3-Benzoyl-6-methyl-2-oxo-2H-pyran-4-yloxymethyl...)
Affinity DataKi:  0.0270nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286326BDBM50286326(2,6-Dichloro-benzoic acid 6-fluoro-4-isopropyl-1,1...)
Affinity DataKi:  0.0300nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039631BDBM50039631(2,6-Dichloro-benzoic acid 4-isopropyl-1,1,3-trioxo...)
Affinity DataKi:  0.0300nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029712BDBM50029712(2-(4-Chloro-5-oxo-2,5-dihydro-furan-3-yloxymethyl)...)
Affinity DataKi:  0.0300nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039631BDBM50039631(2,6-Dichloro-benzoic acid 4-isopropyl-1,1,3-trioxo...)
Affinity DataKi:  0.0300nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039631BDBM50039631(2,6-Dichloro-benzoic acid 4-isopropyl-1,1,3-trioxo...)
Affinity DataKi:  0.0300nMAssay Description:Ratio of Kreact to that of Kinact was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039631BDBM50039631(2,6-Dichloro-benzoic acid 4-isopropyl-1,1,3-trioxo...)
Affinity DataKi:  0.0302nMAssay Description:Observed binding affinity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029713BDBM50029713(4-Isopropyl-6-methoxy-1,1-dioxo-2-(3-oxo-cyclobut-...)
Affinity DataKi:  0.0330nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029691BDBM50029691(2-(2-Benzyl-3-oxo-cyclopent-1-enyloxymethyl)-4-iso...)
Affinity DataKi:  0.0340nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034671BDBM50034671(Phosphoric acid diethyl ester 4-isopropyl-6-methox...)
Affinity DataKi:  0.0350nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288098BDBM50288098(2-Ethoxy-5-ethyl-benzo[d][1,3]oxazin-4-one | CHEMB...)
Affinity DataKi:  0.0430nM Kon:  0.0000145M-1s-1 Koff:  3.39E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285280BDBM50285280(2,6-Dichloro-benzoic acid 4-ethoxy-6-methoxy-1,1,3...)
Affinity DataKi:  0.0490nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029692BDBM50029692(4-Isopropyl-6-methoxy-2-(6-methyl-2-oxo-2H-pyran-4...)
Affinity DataKi:  0.0500nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029695BDBM50029695(4-Isopropyl-6-methoxy-1,1-dioxo-2-(5-oxo-2,5-dihyd...)
Affinity DataKi:  0.0520nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029711BDBM50029711(3-Bromo-2-(4-isopropyl-6-methoxy-1,1,3-trioxo-1,3-...)
Affinity DataKi:  0.0580nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039641BDBM50039641(2,6-Dichloro-benzoic acid 4-sec-butyl-1,1,3-trioxo...)
Affinity DataKi:  0.0600nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50374350BDBM50374350(CHEMBL403098)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029720BDBM50029720(4-Isopropyl-6-methoxy-2-(2-methyl-3-oxo-cyclopent-...)
Affinity DataKi:  0.0600nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061031BDBM50061031((S)-1-[(S)-2-(4-Benzenesulfonylaminocarbonyl-benzo...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity for human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031196BDBM50031196(2-[3-Methyl-2-({1-[3-methyl-2-(4-chlorophenyl-sulf...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029707BDBM50029707(3-Chloro-2-(4-isopropyl-6-methoxy-1,1,3-trioxo-1,3...)
Affinity DataKi:  0.0660nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406288BDBM50406288(CHEMBL344066)
Affinity DataKi:  0.0680nM Kon:  0.0000759M-1s-1 Koff:  1.12E+6s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285286BDBM50285286(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034676BDBM50034676(Phosphoric acid 4-sec-butyl-1,1,3-trioxo-1,3-dihyd...)
Affinity DataKi:  0.0700nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039642BDBM50039642(2,6-Dichloro-benzoic acid 4-ethyl-1,1,3-trioxo-1,3...)
Affinity DataKi:  0.0708nMAssay Description:Observed binding affinity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406293BDBM50406293(CHEMBL356120)
Affinity DataKi:  0.0710nM Kon:  0.0000550M-1s-1 Koff:  7.76E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Sterling Winthrop Pharmaceutical Research Division

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029721BDBM50029721(2-(4-Isopropyl-6-methoxy-1,1,3-trioxo-1,3-dihydro-...)
Affinity DataKi:  0.0780nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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