Compile Data Set for Download or QSAR
Report error Found 174 of ec50 for UniProtKB: P10415
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21424BDBM21424(4-{4-[(2-chlorophenyl)methylidene]piperidin-1-yl}-...)
Affinity DataKi:  0.700nM EC50:  450nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21432BDBM21432(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21434BDBM21434(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  130nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21436BDBM21436(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  130nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21439BDBM21439(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  460nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21440BDBM21440(4-{4-[(2-cyclohexylphenyl)methyl]piperazin-1-yl}-N...)
Affinity DataKi: <1nM EC50:  120nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21441BDBM21441(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  16nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21442BDBM21442(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1nM EC50:  820nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21443BDBM21443(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  460nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21444BDBM21444(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  25nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21445BDBM21445(4-(4-{[2-(2-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nM EC50:  27nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21414BDBM21414(4-{4-[(2-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi: <1nM EC50:  180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21447BDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nM EC50:  8nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21448BDBM21448(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  68nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21449BDBM21449(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  27nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21450BDBM21450(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  13nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21451BDBM21451(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  530nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21421BDBM21421(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  20nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21422BDBM21422(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <1nM EC50:  1.10E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21418BDBM21418(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1.40nM EC50:  200nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21420BDBM21420(4-{4-[(2-bromophenyl)methyl]-4-methoxypiperidin-1-...)
Affinity DataKi:  1.5nM EC50:  200nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21419BDBM21419(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1.60nM EC50:  250nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21415BDBM21415(4-{4-[(3-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi:  1.80nM EC50:  300nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21428BDBM21428(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  2nM EC50:  250nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21426BDBM21426(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  2nM EC50:  210nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21425BDBM21425(4-{4-[(4-chlorophenyl)methylidene]piperidin-1-yl}-...)
Affinity DataKi:  2.10nM EC50:  1.18E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21423BDBM21423(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  2.5nM EC50:  350nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21416BDBM21416(4-{4-[(4-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi:  2.70nM EC50:  500nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 50162774BDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataEC50:  3nMAssay Description:Inhibition of BCL-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21417BDBM21417(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  3.10nM EC50:  100nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21435BDBM21435(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  3.20nM EC50:  950nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21405BDBM21405(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  3.40nM EC50:  600nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21438BDBM21438(4-(4-{[2-(cyclohexylamino)phenyl]methyl}piperazin-...)
Affinity DataKi:  3.5nM EC50:  340nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21433BDBM21433(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  4.5nM EC50:  940nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21437BDBM21437(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  4.60nM EC50:  6.80E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21408BDBM21408(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  6.10nM EC50: >2.00E+4nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21403BDBM21403(4-{3-benzyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl...)
Affinity DataKi:  6.5nM EC50:  2.93E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21413BDBM21413(4-[4-(cyclohexylmethyl)-4-methoxypiperidin-1-yl]-N...)
Affinity DataKi:  6.60nM EC50:  200nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21401BDBM21401(4-(4-benzyl-4-methoxypiperidin-1-yl)-N-[(4-{[(2R)-...)
Affinity DataKi:  8.10nM EC50:  930nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21427BDBM21427(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  9.40nM EC50:  3.60E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21404BDBM21404(4-{4-benzyl-2-methyl-3-oxo-1-oxa-4,8-diazaspiro[4....)
Affinity DataKi:  9.60nM EC50: >5.00E+4nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21429BDBM21429(4-{4-[(2-cyanophenyl)methylidene]piperidin-1-yl}-N...)
Affinity DataKi:  13nM EC50:  1.60E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21411BDBM21411(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  16nM EC50:  1.00E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21446BDBM21446(4-(4-{[2-(3-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  16.9nM EC50:  33nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21412BDBM21412(4-(4-butyl-4-methoxypiperidin-1-yl)-N-[(4-{[(2R)-4...)
Affinity DataKi:  20nM EC50:  3.00E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21402BDBM21402(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  35.2nM EC50: >5.00E+4nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21406BDBM21406(4-(4-benzylpiperazin-1-yl)-N-[(4-{[(2R)-4-(dimethy...)
Affinity DataKi:  39.8nM EC50:  1.70E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21430BDBM21430(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  46nM EC50:  1.38E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21410BDBM21410(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  56nM EC50:  700nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 21407BDBM21407(4-(4-benzoylpiperazin-1-yl)-N-[(4-{[(2R)-4-(dimeth...)
Affinity DataKi:  61.9nM EC50: >5.00E+4nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
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