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Report error Found 2108 for UniProtKB: P36544
LigandPNGBDBM50393244(CHEMBL2151438)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity to human alpha7 nAchRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50364875(CHEMBL1950156)
Affinity DataKi:  0.0920nMAssay Description:Binding affinity to alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393252(CHEMBL2151570)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]A-585539 from alpha7 nAChR human cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393252(CHEMBL2151570)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]A-585539 from alpha7 nAChR in human cerebral cortex membranes after 75 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393251(CHEMBL2151569)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393251(CHEMBL2151569)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399780(CHEMBL2179874)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399779(CHEMBL2179875)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399777(CHEMBL2179877)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393247(CHEMBL1258006)
Affinity DataKi:  1nMAssay Description:Binding affinity to human alpha7 nAChR expressed in HEK293 cells co-expressing RIC3 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393247(CHEMBL1258006)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609510(CHEMBL5276123)
Affinity DataKi:  1nMAssay Description:Binding affinity to alpha7 nAChR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50366779(METHYLLYCACONITINE)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]methyllycaconitine from human alpha-7 in tsA201 cells coexpressed with 5HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50309873(4-(6-Chlorooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...)
Affinity DataKi:  1nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173945(CHEMBL195190 | [2,2']Bithiophenyl-5-carboxylic aci...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399781(CHEMBL2179873)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398820(CHEMBL2177538)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399776(CHEMBL2179878)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50206243(CHEMBL3918431)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398821(CHEMBL2177537)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173953(CHEMBL364069 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50609510(CHEMBL5276123)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to alpha7 nAChR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50190788(CHEMBL378471 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398849(CHEMBL2177553)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50397944(CHEMBL2177512)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173956(CHEMBL370535 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399767(CHEMBL2180253)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM139032(US8884017, 68)
Affinity DataKi:  2nM ΔG°:  -46.2kJ/molepH: 7.4 T: 4°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent

LigandPNGBDBM50190785(CHEMBL378349 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399773(CHEMBL2179881)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in K28 cell membraneMore data for this Ligand-Target Pair
LigandPNGBDBM50399770(CHEMBL2180250)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50433470(CHEMBL2380928)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-methyllycaconitine from human alpha7 nAChR transfected in human SH-SY5Y cells after 240 mins by liquid scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50417105(CHEMBL1258240)
Affinity DataKi:  2.69nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]epibatidine from alpha7 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting metho...More data for this Ligand-Target Pair
LigandPNGBDBM50393247(CHEMBL1258006)
Affinity DataKi:  2.75nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399792(CHEMBL2179862)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM139033(US8884017, 73)
Affinity DataKi:  2.80nM ΔG°:  -45.4kJ/molepH: 7.4 T: 4°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent

LigandPNGBDBM50393249(CHEMBL2151441)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes after 2 hrs by topcount scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  3nMAssay Description:Binding affinity to human alpha7 nAchRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM139027(US8884017, 58)
Affinity DataKi:  3.10nM ΔG°:  -45.1kJ/molepH: 7.4 T: 4°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent

LigandPNGBDBM50309888(4-(6-Chloro-5-methyloxazolo[4,5-b]pyridin-2-yl)-1,...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398850(CHEMBL2177552)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173942(CHEMBL195329 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50173943(5-Phenyl-thiophene-2-carboxylic acid (1-aza-bicycl...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398849(CHEMBL2177553)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM139020(US8884017, 35)
Affinity DataKi:  3.70nM ΔG°:  -44.7kJ/molepH: 7.4 T: 4°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent

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