Compile Data Set for Download or QSAR
maximum 50k data
Found 244 of ki for UniProtKB: P00533
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50238182(CHEMBL4100860)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of binding of [3H][D-Ala2,D-Leu5]enkephalin to Opioid receptor delta 1 in the rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of wild-type EGFR (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR catalytic domain (669 to 1210 residues) expressed in baculovirus expression system by mass...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50210162(CHEMBL3883534)
Affinity DataKi:  0.140nMAssay Description:Inhibition of PF-06422899 binding to EGFR in human A431 cells after 1 hr by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50238177(CHEMBL4098072)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50498973(CHEMBL3734934)
Affinity DataKi: >0.530nMAssay Description:Inhibition of human wild type EGFR using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substrate measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50141636(CHEMBL3758502)
Affinity DataKi:  0.600nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50141610(CHEMBL3759096)
Affinity DataKi:  1.10nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50141902(CHEMBL3758602)
Affinity DataKi:  1.5nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50236369((R)-1-morpholino-2-(4-(1-(thiazol-2-ylmethyl)-1H-i...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50238183(CHEMBL4071012)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450885(CHEMBL4216749)
Affinity DataKi:  2nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50112173(CHEMBL3608429)
Affinity DataKi:  2nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450887(CHEMBL4211367)
Affinity DataKi:  3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataKi:  3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450884(CHEMBL4211782)
Affinity DataKi:  3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50221531(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450886(CHEMBL4206481)
Affinity DataKi:  4nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50237140(CHEMBL4068763)
Affinity DataKi:  5.10nMAssay Description:Reversible inhibition of wild-type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 end amino acid residues) expressed in baculovirus...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450871(CHEMBL4205392)
Affinity DataKi:  6nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50141611(CHEMBL3758739)
Affinity DataKi:  6.5nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50337385(5-(1-(1-benzylpyrrolidin-3-yl)-4-(4-fluorophenyl)-...)
Affinity DataKi:  8nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450868(CHEMBL4216679)
Affinity DataKi:  8nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50221516(6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...)
Affinity DataKi:  8.40nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450875(CHEMBL4208811)
Affinity DataKi:  9nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450870(Mavelertinib | PF-06747775)
Affinity DataKi:  13nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataKi:  14nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataKi:  14nMAssay Description:Reversible inhibition of wild-type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 end amino acid residues) expressed in baculovirus...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50112176(CHEMBL3608432)
Affinity DataKi:  17nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50337383(4-(2-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi:  17nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450866(CHEMBL4208829)
Affinity DataKi:  18nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50157333(CHEMBL3781433)
Affinity DataKi:  18nMAssay Description:Inhibition of human N-terminal GST-tagged EGFR catalytic domain (669 to 1210 residues) expressed in baculovirus expression system using Fl-EEPLYWSFPA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450869(CHEMBL4218154)
Affinity DataKi:  19nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50532909(CHEMBL4527443)
Affinity DataKi:  22nMAssay Description:Inhibition of EGFR kinase domain L858R/T790M mutant (unknown origin) by enzyme kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50532909(CHEMBL4527443)
Affinity DataKi:  22nMAssay Description:Inhibition of EGFR kinase domain L858R/T790M mutant (unknown origin) by enzyme kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50221518(6,7-dimethoxy-4-((1R,2S)-2-phenylcyclopropylamino)...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi:  27nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50315893(CHEMBL1090356 | N-(3-(5-(2-(4-morpholinophenylamin...)
Affinity DataKi:  32nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450873(CHEMBL4206312)
Affinity DataKi:  32nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50141610(CHEMBL3759096)
Affinity DataKi:  34nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50555575(C-18112003-G | GNS-1480 | GNS1480 | JNJ-73841937-A...)
Affinity DataKi:  34nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50396071(CHEMBL2170582 | US10828301, Compound R921303)
Affinity DataKi:  35nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50450865(CHEMBL4212326)
Affinity DataKi:  36nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50221535(4-((1R,2S)-2-(2-fluorophenyl)cyclopropylamino)-6,7...)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50157358(CHEMBL3780553)
Affinity DataKi:  37nMAssay Description:Inhibition of human N-terminal GST-tagged EGFR catalytic domain (669 to 1210 residues) expressed in baculovirus expression system using Fl-EEPLYWSFPA...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50221522(6-(4-(aminomethyl)phenyl)-4-((1R,2S)-2-phenylcyclo...)
Affinity DataKi:  40nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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