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TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519933BDBM50519933(CHEMBL4444007)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155523BDBM155523(US9011882, Table 1, Compound 18)
Affinity DataIC50: 3.30E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50389868BDBM50389868(CHEMBL2070857 | US9011882, Table 1, Compound 16)
Affinity DataIC50: 5.10E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155517BDBM155517(US9011882, Table 1, Compound 10)
Affinity DataIC50: 7.10E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155515BDBM155515(US9011882, Table 1, Compound 8)
Affinity DataIC50: 8.60E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565138BDBM50565138(PD-404182 | CHEMBL595227)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human DDAH1 using SMTC as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155510BDBM155510(US9011882, Table 1, Compound 3)
Affinity DataIC50: 9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34513BDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataIC50: 9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155521BDBM155521(US9011882, Table 1, Compound 14)
Affinity DataIC50: 1.05E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155519BDBM155519(US9011882, Table 1, Compound 12)
Affinity DataIC50: 1.10E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155522BDBM155522(US9011882, Table 1, Compound 17)
Affinity DataIC50: 1.18E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240715BDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155516BDBM155516(US9011882, Table 1, Compound 9)
Affinity DataIC50: 1.28E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240715BDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 141899BDBM141899(hDDAH inhibitor, 2a | US8921421, L-257)
Affinity DataKi:  1.30E+4nM IC50: 2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155508BDBM155508(US9011882, Table 1, Compound 1)
Affinity DataIC50: 1.31E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46658BDBM46658(MLS-0254244.0001 | cid_17520 | 1,2-benzothiazol-3-...)
Affinity DataIC50: 1.32E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155520BDBM155520(US9011882, Table 1, Compound 13)
Affinity DataIC50: 1.34E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155514BDBM155514(US9011882, Table 1, Compound 7)
Affinity DataIC50: 1.37E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155518BDBM155518(US9011882, Table 1, Compound 11)
Affinity DataIC50: 1.41E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155512BDBM155512(US9011882, Table 1, Compound 5)
Affinity DataIC50: 1.77E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626259BDBM50626259(CHEMBL5437726)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 141900BDBM141900(US8921421, 3)
Affinity DataKi:  1.80E+4nM IC50: 7.00E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155511BDBM155511(US9011882, Table 1, Compound 4)
Affinity DataIC50: 2.12E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155509BDBM155509(US9011882, Table 1, Compound 2)
Affinity DataIC50: 2.33E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240959BDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626258BDBM50626258(CHEMBL5410984)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155524BDBM155524(US9011882, Table 1, Compound 19)
Affinity DataIC50: 3.99E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 155513BDBM155513(US9011882, Table 1, Compound 6)
Affinity DataIC50: 4.58E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242402BDBM50242402(4-Hydroxynonenal | 4-hydroxy-2-nonenal | CHEMBL454...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human DDAH1 expressed in Escherichia coli measured after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070208BDBM50070208(CHEBI:6375 | A-65006 | AG-1749 | Lansoprazole | Pr...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of recombinant human DDAH1 by HTS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070209BDBM50070209(CHEBI:8768 | Aciphex | LY-307640 | Rabeprazole)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant DDAH1 reduction in L-citrulline formation using ADMA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254452BDBM50254452(N-omega-propargyl-L-arginine | CHEMBL197234)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254452BDBM50254452(N-omega-propargyl-L-arginine | CHEMBL197234)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255074BDBM50255074(N5-(1-iminobutyl)-L-ornithine | (S)-2-Amino-5-buty...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255074BDBM50255074(N5-(1-iminobutyl)-L-ornithine | (S)-2-Amino-5-buty...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254449BDBM50254449(N5-(1-iminopent-3-enyl)-L-ornithine | CHEMBL456882)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254449BDBM50254449(N5-(1-iminopent-3-enyl)-L-ornithine | CHEMBL456882)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626261BDBM50626261(CHEMBL5434286)
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254451BDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254451BDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240714BDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240714BDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626260BDBM50626260(CHEMBL5438148)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626257BDBM50626257(CHEMBL364952)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DDAH1 using [14C]-L-NMMA as substrate assessed as reduction in [14C]-citrulline conversion measured after 1 hrs by by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240716BDBM50240716(Nomega-propyl-L-arginine | N-omega-propyl-L-argini...)
Affinity DataIC50: 2.83E+5nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240716BDBM50240716(Nomega-propyl-L-arginine | N-omega-propyl-L-argini...)
Affinity DataIC50: 2.83E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254450BDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626267BDBM50626267(CHEMBL5433812)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of human DDAH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242405BDBM50242405((2S)-2-amino-4-sulfanylbutanoic acid | L-homocyste...)
Affinity DataIC50: 6.40E+5nMAssay Description:Inhibition of human recombinant DDAH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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