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TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626264BDBM50626264(CHEMBL5423612)
Affinity DataKi:  190nMAssay Description:Inhibition of N-terminal His6-tagged human DDAH1 expressed in Escherichia coli BL21 DE3 cells using L-Nva as substrate assessed as L-citrulline forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519933BDBM50519933(CHEMBL4444007)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519933BDBM50519933(CHEMBL4444007)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate assessed as inhibition constant preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519934BDBM50519934(CHEMBL4461206)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519934BDBM50519934(CHEMBL4461206)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human DDAH1 transfected in HEK293T cells assessed as inhibition constant measured after 15 mins in presence of N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240715BDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240715BDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 expressed using SMTC as substrate assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240715BDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235685BDBM235685(hDDAH inhibitor, 1a)
Affinity DataKi:  2.00E+3nM ΔG°:  -8.08kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240715BDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626259BDBM50626259(CHEMBL5437726)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate assessed as inhibition constant preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92904BDBM92904(nNOS and DDAH inhibitor, 14)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626262BDBM50626262(CHEMBL1234051)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged human DDAH1 expressed in Escherichia coli Rosetta 2 DE3 cells assessed as inhibition constant by calorimetric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519932BDBM50519932(CHEMBL4449638)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626268BDBM50626268(CHEMBL5427675)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of His-tagged human DDAH1 using SMTC as substrate assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240959BDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 141899BDBM141899(hDDAH inhibitor, 2a | US8921421, L-257)
Affinity DataKi:  1.30E+4nM ΔG°:  -6.93kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240959BDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 141899BDBM141899(hDDAH inhibitor, 2a | US8921421, L-257)
Affinity DataKi:  1.30E+4nM IC50: 2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626258BDBM50626258(CHEMBL5410984)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate assessed as inhibition constant preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254452BDBM50254452(N-omega-propargyl-L-arginine | CHEMBL197234)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235691BDBM235691(hDDAH inhibitor, 2e)
Affinity DataKi:  1.70E+4nM ΔG°:  -6.76kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254452BDBM50254452(N-omega-propargyl-L-arginine | CHEMBL197234)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 141900BDBM141900(US8921421, 3)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 141900BDBM141900(US8921421, 3)
Affinity DataKi:  1.80E+4nM IC50: 7.00E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255074BDBM50255074(N5-(1-iminobutyl)-L-ornithine | (S)-2-Amino-5-buty...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255074BDBM50255074(N5-(1-iminobutyl)-L-ornithine | (S)-2-Amino-5-buty...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 152700BDBM152700((S)-2-Amino-5-butyrimidamidopentanoic acid (9) | h...)
Affinity DataKi:  3.20E+4nM ΔG°:  -6.37kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254449BDBM50254449(N5-(1-iminopent-3-enyl)-L-ornithine | CHEMBL456882)
Affinity DataKi:  3.60E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235686BDBM235686(hDDAH inhibitor, 1c)
Affinity DataKi:  3.60E+4nM ΔG°:  -6.30kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254449BDBM50254449(N5-(1-iminopent-3-enyl)-L-ornithine | CHEMBL456882)
Affinity DataKi:  3.60E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626262BDBM50626262(CHEMBL1234051)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human DDAH1 expressed using SMTC as substrate assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254450BDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50626263BDBM50626263(CHEMBL5440688)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human DDAH1 expressed using SMTC as substrate assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254450BDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254451BDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235690BDBM235690(hDDAH inhibitor, 2d)
Affinity DataKi:  5.70E+4nM ΔG°:  -6.02kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254451BDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254451BDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240714BDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235689BDBM235689(hDDAH inhibitor, 2c)
Affinity DataKi:  5.80E+4nM ΔG°:  -6.01kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240714BDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519930BDBM50519930(CHEMBL4544147)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519936BDBM50519936(CHEMBL4442120)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235688BDBM235688(hDDAH inhibitor, 2b)
Affinity DataKi:  9.00E+4nM ΔG°:  -5.74kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240716BDBM50240716(Nomega-propyl-L-arginine | N-omega-propyl-L-argini...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240716BDBM50240716(Nomega-propyl-L-arginine | N-omega-propyl-L-argini...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519934BDBM50519934(CHEMBL4461206)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human DDAH1 expressed using SMTC as substrate assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92905BDBM92905(DDAH Inhibitor, 15)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565138BDBM50565138(PD-404182 | CHEMBL595227)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human DDAH1 expressed using SMTC as substrate assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
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