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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102777(US8541572, 2207)
Affinity DataKi:  0.0300nM IC50:  260nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102624(US8541572, 303)
Affinity DataKi:  0.0300nM IC50:  383nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102623(US8541572, 302)
Affinity DataKi:  0.0521nM IC50:  723nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102666(US8541572, 973)
Affinity DataKi:  0.0524nM IC50:  61nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102663(US8541572, 970)
Affinity DataKi:  0.0556nM IC50:  65nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102802(US8541572, 2234)
Affinity DataKi:  0.0600nM IC50:  678nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102680(US8541572, 987)
Affinity DataKi:  0.0627nM IC50:  75.4nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102845(US8541572, 927)
Affinity DataKi:  0.0630nM IC50:  151nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102664(US8541572, 971)
Affinity DataKi:  0.0651nM IC50:  80.3nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102840(US8541572, 922)
Affinity DataKi:  0.0720nM IC50:  92nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50332292((R)-5-((4-(3-hydroxypyridin-2-yl)phenyl)ethynyl)-5...)
Affinity DataKi:  0.0740nM IC50:  117nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102698(US8541572, 1008)
Affinity DataKi:  0.0762nM IC50:  342nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102695(US8541572, 1002)
Affinity DataKi:  0.0770nM IC50:  119nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102694(US8541572, 1001)
Affinity DataKi:  0.0781nM IC50:  106nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102696(US8541572, 1003)
Affinity DataKi:  0.0826nM IC50:  124nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102855(US8541572, 943)
Affinity DataKi:  0.0830nM IC50:  65nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102852(US8541572, 936)
Affinity DataKi:  0.0930nM IC50:  72.4nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102843(US8541572, 925)
Affinity DataKi:  0.0930nM IC50:  74nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102679(US8541572, 986)
Affinity DataKi:  0.0973nM IC50:  87nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102669(CHEMBL1288726 | US8541572, 976)
Affinity DataKi:  0.0988nM IC50:  39.8nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102863(US8541572, 2257)
Affinity DataKi:  0.100nM IC50:  490nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102844(US8541572, 926)
Affinity DataKi:  0.110nM IC50:  76nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102873(US8541572, 2267)
Affinity DataKi:  0.110nM IC50:  134nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102747(US8541572, 1918)
Affinity DataKi:  0.110nM IC50:  936nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102681(US8541572, 988)
Affinity DataKi:  0.115nM IC50:  55.9nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102731(US8541572, 1902)
Affinity DataKi:  0.120nM IC50:  127nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102857(US8541572, 946)
Affinity DataKi:  0.120nM IC50:  154nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102858(US8541572, 951)
Affinity DataKi:  0.120nM IC50:  220nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102872(US8541572, 2266)
Affinity DataKi:  0.120nM IC50:  927nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102853(US8541572, 941)
Affinity DataKi:  0.130nM IC50:  100nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102730(US8541572, 1901)
Affinity DataKi:  0.130nM IC50:  113nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102846(US8541572, 928)
Affinity DataKi:  0.150nM IC50:  278nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102789(US8541572, 2220)
Affinity DataKi:  0.150nM IC50:  417nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102800(US8541572, 2233)
Affinity DataKi:  0.150nM IC50:  811nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102834(US8541572, 911)
Affinity DataKi:  0.160nM IC50:  20nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102835(US8541572, 912)
Affinity DataKi:  0.160nM IC50:  153nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102784(US8541572, 2215)
Affinity DataKi:  0.160nM IC50:  229nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102819(US8541572, 2252)
Affinity DataKi:  0.160nM IC50:  258nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102738(US8541572, 1909)
Affinity DataKi:  0.170nM IC50:  78nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102856(US8541572, 945)
Affinity DataKi:  0.170nM IC50:  86nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102806(US8541572, 2239)
Affinity DataKi:  0.170nM IC50:  188nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102829(US8541572, 906)
Affinity DataKi:  0.170nM IC50:  382nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102720(US8541572, 1311)
Affinity DataKi:  0.180nM IC50:  69nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102736(US8541572, 1907)
Affinity DataKi:  0.180nM IC50:  86nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102861(US8541572, 954)
Affinity DataKi:  0.180nM IC50:  87nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102839(US8541572, 916)
Affinity DataKi:  0.180nM IC50:  274nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102832(US8541572, 909)
Affinity DataKi:  0.180nM IC50:  292nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102718(US8541572, 1309)
Affinity DataKi:  0.190nM IC50:  42nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102849(US8541572, 931)
Affinity DataKi:  0.190nM IC50:  47nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102715(US8541572, 1306)
Affinity DataKi:  0.190nM IC50:  169nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent

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