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TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123745(CHEMBL3622746)
Affinity DataKi:  1nMAssay Description:Competitive inhibition of human 15-LOX-1 assessed as reduction in conversion of linoleic acid to 13(S)-HpODE incubated for 10 mins followed by linole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123745(CHEMBL3622746)
Affinity DataKi:  1nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026174(CHEMBL1271117)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026089(CHEMBL1270505)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50329322(4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)bu...)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026088(CHEMBL1271322)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026086(CHEMBL1270606)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026085(CHEMBL1269896)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026081(CHEMBL1270112)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026082(CHEMBL1270912)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026087(CHEMBL1270218)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50329323(4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)bu...)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026091(CHEMBL1270506)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026170(CHEMBL1271429)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026084(CHEMBL1271012)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026174(CHEMBL1271117)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026078(CHEMBL1271219)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026083(CHEMBL1270004)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026079(CHEMBL1270507)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50026080(CHEMBL1270311)
Affinity DataKi: <10nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 after 15 mins by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417172(CHEMBL1269897)
Affinity DataKi:  15nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417174(CHEMBL1270705)
Affinity DataKi:  15nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417175(CHEMBL1271321)
Affinity DataKi:  16nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM22302(N-{2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}-4...)
Affinity DataKi:  21nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)
Affinity DataKi:  22nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417161(CHEMBL1270914)
Affinity DataKi:  23nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417155(CHEMBL1270412)
Affinity DataKi:  26nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417167(CHEMBL1271222)
Affinity DataKi:  26nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417170(CHEMBL1270219)
Affinity DataKi:  27nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123669(CHEMBL3622735)
Affinity DataKi:  30nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417154(CHEMBL1270913)
Affinity DataKi:  31nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417177(CHEMBL1270003)
Affinity DataKi:  33nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123669(CHEMBL3622735)
Affinity DataKi:  36nMAssay Description:Competitive inhibition of human 15-LOX-1 assessed as reduction in conversion of linoleic acid to 13(S)-HpODE incubated for 10 mins followed by linole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417156(CHEMBL1270413)
Affinity DataKi:  43nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417157(CHEMBL1270607)
Affinity DataKi:  57nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123798(CHEMBL235920)
Affinity DataKi:  73nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123798(CHEMBL235920)
Affinity DataKi:  73nMAssay Description:Competitive inhibition of human 15-LOX-1 assessed as reduction in conversion of linoleic acid to 13(S)-HpODE incubated for 10 mins followed by linole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM79955(1H-indole-4-carboxylic acid 4-[[5-(1-naphthalenyl)...)
Affinity DataKi:  76nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123672(CHEMBL3622738)
Affinity DataKi:  80nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417160(CHEMBL1270811)
Affinity DataKi:  81nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417159(CHEMBL1270707)
Affinity DataKi:  82nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417152(CHEMBL1270504)
Affinity DataKi:  85nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123673(CHEMBL3622739)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate assessed as equilibrium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417171(CHEMBL1270313)
Affinity DataKi:  100nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123670(CHEMBL3622736)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417162(CHEMBL1270915)
Affinity DataKi:  140nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123671(CHEMBL3622737)
Affinity DataKi:  170nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50417151(CHEMBL1270410)
Affinity DataKi:  170nMAssay Description:Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123674(CHEMBL3622740)
Affinity DataKi:  210nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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