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Found 146 of ic50 for UniProtKB: P70597
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252472(CHEMBL4085914)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260732(CHEMBL4105205)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252483(CHEMBL4081524)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252452(CHEMBL4074797)
Affinity DataIC50:  6.40nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260740(CHEMBL4100262)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240170(CHEMBL4064816)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240170(CHEMBL4064816)
Affinity DataIC50:  9.40nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252462(CHEMBL4104333)
Affinity DataIC50:  9.90nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260656(CHEMBL4083796)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119458(US8680120, 9-32)
Affinity DataIC50:  11nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)
Affinity DataIC50:  12.6nMAssay Description:Binding affinity to rat EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119460(US8680120, 9-43)
Affinity DataIC50:  13nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119456(US8680120, 9-21)
Affinity DataIC50:  13nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252484(CHEMBL4059569)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260658(CHEMBL4091580)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252509(CHEMBL4060696)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119468(US8680120, 25-18)
Affinity DataIC50:  17nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119471(US8680120, 25-26)
Affinity DataIC50:  17nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260657(CHEMBL4062060)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119461(US8680120, 9-44)
Affinity DataIC50:  19nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260660(CHEMBL4088835)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119453(US8680120, 9-1)
Affinity DataIC50:  21nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252464(CHEMBL4081022)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419410(CHEMBL1915252)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119455(US8680120, 9-15)
Affinity DataIC50:  22nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119479(US8680120, 25-38)
Affinity DataIC50:  22nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119459(US8680120, 9-35)
Affinity DataIC50:  23nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119481(US8680120, 25-41)
Affinity DataIC50:  25nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119473(US8680120, 25-29)
Affinity DataIC50:  26nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119478(US8680120, 25-37)
Affinity DataIC50:  27nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119472(US8680120, 25-28)
Affinity DataIC50:  28nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119482(US8680120, 25-42)
Affinity DataIC50:  28nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260702(CHEMBL4089536)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252510(CHEMBL4076413)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252481(CHEMBL4079088)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252494(CHEMBL4105272)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252465(CHEMBL4088913)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119470(US8680120, 25-23)
Affinity DataIC50:  32nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119467(US8680120, 25-17)
Affinity DataIC50:  32nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252492(CHEMBL4062313)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119474(US8680120, 25-31)
Affinity DataIC50:  33nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119463(US8680120, 25-11)
Affinity DataIC50:  34nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119457(US8680120, 9-25)
Affinity DataIC50:  35nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119477(US8680120, 25-36)
Affinity DataIC50:  35nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119469(US8680120, 25-19)
Affinity DataIC50:  36nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252508(CHEMBL4096603)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119480(US8680120, 25-39)
Affinity DataIC50:  37nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119465(US8680120, 25-13)
Affinity DataIC50:  38nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM119466(US8680120, 25-16)
Affinity DataIC50:  39nMAssay Description:The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252480(CHEMBL4097108)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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