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TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)
Affinity DataKi:  0.0610nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50024382(CHEMBL189690)
Affinity DataKi:  0.0794nMAssay Description:Inhibition of MOCAc-Pro-Leu-Gly-Leu-A2p (Dnp)-Ala-Arg-NH2 binding to human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50109635((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  0.0800nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143729((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)
Affinity DataKi:  0.0970nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50024388(CHEMBL190621)
Affinity DataKi:  0.100nMAssay Description:Inhibition of MOCAc-Pro-Leu-Gly-Leu-A2p (Dnp)-Ala-Arg-NH2 binding to human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50109621(CHEMBL425316 | [4-(4-Amino-phenoxy)-phenyl]-(3-hyd...)
Affinity DataKi:  0.100nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50563342(CHEMBL4797032)
Affinity DataKi:  0.110nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human MMP-9 assessed as inhibition constant using MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11873(N-Hydroxy-1-methyl-4-{[4-(phenoxyphenyl]sulfonyl}-...)
Affinity DataKi:  0.290nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11870(4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy ...)
Affinity DataKi:  0.300nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50024390(CHEMBL372702)
Affinity DataKi:  0.310nMAssay Description:Inhibition of MOCAc-Pro-Leu-Gly-Leu-A2p (Dnp)-Ala-Arg-NH2 binding to human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50031790((R)-N*4*-Hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of human Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50109626(Biphenyl-4-yl-(3-hydroxycarbamoyl-3,4-dihydro-1H-i...)
Affinity DataKi:  0.310nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11877(N-Hydroxy-4-{[4-(phenoxyphenyl]sulfonyl}-1- (2-pro...)
Affinity DataKi:  0.400nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062304((R)-2-Hexyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...)
Affinity DataKi:  0.410nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50088126(CHEMBL293528 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062345((R)-2-Butyl-N*4*-hydroxy-N*1*-[(S)-2-(1H-indol-3-y...)
Affinity DataKi:  0.540nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataKi:  0.550nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  0.570nMAssay Description:Inhibition of MMP-9 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062311((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-1-(3-morphol...)
Affinity DataKi:  0.580nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataKi:  0.580nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11870(4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy ...)
Affinity DataKi:  0.580nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50024402(CHEMBL190232)
Affinity DataKi:  0.600nMAssay Description:Inhibition of MOCAc-Pro-Leu-Gly-Leu-A2p (Dnp)-Ala-Arg-NH2 binding to human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50109625((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11875(1-Cyclopropyl-N-hydroxy-4-{[4-(phenoxyphenyl]-sulf...)
Affinity DataKi:  0.600nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11360(Hydroxamate 41 | N-hydroxy-2-{[(4-nitrophenyl)meth...)
Affinity DataKi:  0.600nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11354(Hydroxamate 35 | N-Pentafluorophenylsulfonyl-N-4-n...)
Affinity DataKi:  0.600nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50086781(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.603nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.603nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062318((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  0.630nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062294((R)-N*4*-Hydroxy-N*1*-{(S)-2-(1H-indol-3-yl)-1-[(p...)
Affinity DataKi:  0.680nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50088109(CHEMBL55521 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062336((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  0.700nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50160855(1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM11874(N-Hydroxy-1-(2-methoxyethyl)-4-{[4-(phenoxyphenyl]...)
Affinity DataKi:  0.700nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50160855(1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro...)
Affinity DataKi:  0.720nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50160851(4-[4-(2,6,8,10-Tetraoxo-1,7,9-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.720nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50160851(4-[4-(2,6,8,10-Tetraoxo-1,7,9-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.724nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50160855(1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro...)
Affinity DataKi:  0.724nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062293((R)-N*4*-Hydroxy-N*1*-[(S)-1-(2-hydroxy-ethylcarba...)
Affinity DataKi:  0.760nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50062353((R)-N*4*-Hydroxy-N*1*-{(S)-2-(1H-indol-3-yl)-1-[(p...)
Affinity DataKi:  0.780nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50088065(CHEMBL54054 | N-Hydroxy-2-[(4-nitro-benzyl)-(3-tri...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50563341(CHEMBL4800470)
Affinity DataKi:  0.830nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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