Compile Data Set for Download or QSAR
Found 6 of kd for UniProtKB: P19020
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50043603(7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro...)
Show SMILES CCCN(C\C=C\I)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+/t15-/m1/s1
Affinity DataKd:  0.0500nMAssay Description:Binding affinity was tested against dopamine receptor D3 in Sf9 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@@H]1CCN(Cc2ccccc2)[C@@H]1C
Show InChI InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m1/s1
Affinity DataKd:  0.0600nMAssay Description:Binding affinity to Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cells after 1 hr by ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@@H]1CCN(Cc2ccccc2)[C@@H]1C
Show InChI InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m1/s1
Affinity DataKd:  0.0640nMAssay Description:Binding affinity to Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr by beta scintill...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Show SMILES CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+
Affinity DataKd:  0.130nMAssay Description:Binding affinity was tested against dopamine receptor D3 in the absence of NaClMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Show SMILES CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+
Affinity DataKd:  0.480nMAssay Description:Binding affinity was tested against dopamine receptor D3 in rat striatal membarane homogenateMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020222((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Show SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3
Affinity DataKd:  0.670nMAssay Description:Tested for binding affinity against dopamine receptor D3More data for this Ligand-Target Pair