Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ic50 data for polymerid = 6516
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50600961(CHEMBL5198892)
Affinity DataIC50:  0.220nMAssay Description:Displacement of [18F]-LU13 from rat spleen CB2 receptor incubated for 90 mins by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50375382(CHEMBL410014)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50341951(((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-...)
Affinity DataIC50:  6.30nMAssay Description:Agonist activity at rat CB2 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP production treated 15 mins before fors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50379695(CHEMBL2010898)
Affinity DataIC50:  9.33nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50379694(CHEMBL2010900)
Affinity DataIC50:  9.55nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50340310((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Affinity DataIC50:  11nMAssay Description:Agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50340319(CHEMBL1760939 | N-((1-(hydroxymethyl)cyclopentyl)m...)
Affinity DataIC50:  58nMAssay Description:Agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50341952(((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-...)
Affinity DataIC50:  81nMAssay Description:Agonist activity at rat CB2 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP production treated 15 mins before fors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50492813(CHEMBL2414609)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in rat spleen homogenate after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50492812(CHEMBL2414612)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in rat spleen homogenate after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50492811(CHEMBL2414610)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in rat spleen homogenate after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50251193(3-[3-Benzyl-[1,2,4]oxadiazol-5-yl]-1-(2-morpholin-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50316513(CHEMBL1096182 | N-((4R)-6-(4-chlorophenyl)-7-(2,4-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of rat cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50379695(CHEMBL2010898)
Affinity DataIC50:  1.55E+3nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in HEK293 cells co-expressing chimeric Gaq/o protein by FLIPR assay by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50260494(4-(2-(3-(3-(4-Methoxybenzyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50251194(4-(2-(3-(3-Phenyl-1,2,4-oxadiazol-5-yl)-1H-indol-1...)
Affinity DataIC50:  4.03E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50267713(CHEMBL522123 | N-(cyclopropylmethyl)-11-(3,5-dihyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor in rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50267670(CHEMBL490046 | N-cyclopropyl-11-(3,5-dihydroxyphen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor in rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50379692(CHEMBL2010907)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50267637(11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydrox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50267670(CHEMBL490046 | N-cyclopropyl-11-(3,5-dihydroxyphen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50267713(CHEMBL522123 | N-(cyclopropylmethyl)-11-(3,5-dihyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50267637(11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydrox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor in rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL
LigandPNGBDBM50379693(CHEMBL2010905)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed