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TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663841(US20240109915, Example 22)
Affinity DataIC50:  0.900nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663852(US20240109915, Example 34)
Affinity DataIC50:  1.30nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663855(US20240109915, Example 37)
Affinity DataIC50:  1.30nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663858(US20240109915, Example 40)
Affinity DataIC50:  1.5nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663912(US20240109915, Example 97)
Affinity DataIC50:  1.80nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663833(US20240109915, Example 14)
Affinity DataIC50:  2.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663869(US20240109915, Example 52)
Affinity DataIC50:  2.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663907(US20240109915, Example 92)
Affinity DataIC50:  2.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663853(US20240109915, Example 35)
Affinity DataIC50:  2.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663915(US20240109915, Example 100)
Affinity DataIC50:  3.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663860(US20240109915, Example 42)
Affinity DataIC50:  3.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663843(US20240109915, Example 24)
Affinity DataIC50:  3.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663837(US20240109915, Example 18)
Affinity DataIC50:  3.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663834(US20240109915, Example 15)
Affinity DataIC50:  3.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663871(US20240109915, Example 55)
Affinity DataIC50:  3.5nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663850(US20240109915, Example 32)
Affinity DataIC50:  3.5nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663840(US20240109915, Example 21)
Affinity DataIC50:  3.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663878(US20240109915, Example 62)
Affinity DataIC50:  3.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663914(US20240109915, Example 99)
Affinity DataIC50:  3.90nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663883(US20240109915, Example 68)
Affinity DataIC50:  3.90nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663849(US20240109915, Example 31)
Affinity DataIC50:  4nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663894(US20240109915, Example 79)
Affinity DataIC50:  4.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663877(US20240109915, Example 61)
Affinity DataIC50:  4.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663830(US20240109915, Example 11)
Affinity DataIC50:  4.5nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663848(US20240109915, Example 30)
Affinity DataIC50:  4.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663885(US20240109915, Example 70)
Affinity DataIC50:  4.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663856(US20240109915, Example 38)
Affinity DataIC50:  4.90nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663851(US20240109915, Example 33)
Affinity DataIC50:  5.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663831(US20240109915, Example 12 | US20240109915, Example...)
Affinity DataIC50:  5.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663861(US20240109915, Example 43)
Affinity DataIC50:  5.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663831(US20240109915, Example 12 | US20240109915, Example...)
Affinity DataIC50:  5.30nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663867(US20240109915, Example 50)
Affinity DataIC50:  5.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663918(US20240109915, Example 103)
Affinity DataIC50:  5.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663827(US20240109915, Example 8)
Affinity DataIC50:  5.5nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663923(US20240109915, Example 108)
Affinity DataIC50:  5.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663872(US20240109915, Example 56)
Affinity DataIC50:  5.80nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663897(US20240109915, Example 82)
Affinity DataIC50:  6.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663902(US20240109915, Example 87)
Affinity DataIC50:  6.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663846(US20240109915, Example 28)
Affinity DataIC50:  6.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663904(US20240109915, Example 89)
Affinity DataIC50:  6.30nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663866(US20240109915, Example 49)
Affinity DataIC50:  6.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663857(US20240109915, Example 39)
Affinity DataIC50:  6.40nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663844(US20240109915, Example 25)
Affinity DataIC50:  6.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663919(US20240109915, Example 104)
Affinity DataIC50:  6.70nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663900(US20240109915, Example 85)
Affinity DataIC50:  7nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663874(US20240109915, Example 58)
Affinity DataIC50:  7.10nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663917(US20240109915, Example 102)
Affinity DataIC50:  7.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663842(US20240109915, Example 23)
Affinity DataIC50:  7.20nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663835(US20240109915, Example 16)
Affinity DataIC50:  7.30nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetActivating signal cointegrator 1 complex subunit 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM663862(US20240109915, Example 45)
Affinity DataIC50:  7.60nMAssay Description:The ACC inhibitory activity of the compounds of the present invention was demonstrated by methods based on standard procedures. The direct inhibition...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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