Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 1755 of ki for UniProtKB: P23944
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033109(2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity against Alpha-1D adrenergic receptor, from rat clones.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122243(4-Chloro-5-[4-(furan-2-carbonyl)-piperazin-1-yl]-2...)
Affinity DataKi:  0.0520nMAssay Description:Binding affinity towards Alpha-1 adrenergic receptor in rat cerebral cortex using [3H]prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50230846(CHEMBL2114071)
Affinity DataKi:  0.0680nMAssay Description:Binding affinity against alpha-1 adrenergic receptor by measuring displacement of [3H]prazosin from rat brain cortex membranes (in vitro).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50230859(CHEMBL309150)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity against alpha-1 adrenergic receptor by measuring displacement of [3H]prazosin from rat brain cortex membranes (in vitro).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataKi:  0.0700nMAssay Description:In vitro binding affinity using [3H]-prazosin as radioligand against adrenoceptor alpha 1d expressed in LTK cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataKi:  0.0760nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226239(CHEMBL50451)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity against alpha-1-adrenoceptor in rat brain homogenates [3H]-prazosin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328496(11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenzo[b...)
Affinity DataKi:  0.0840nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226814(CHEMBL6424)
Affinity DataKi:  0.100nMAssay Description:In vitro binding affinity determined for alpha-1 adrenergic receptor by the displacement of [3H]- prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143673(8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50230848(CHEMBL70872)
Affinity DataKi:  0.110nMAssay Description:Binding affinity against alpha-1 adrenergic receptor by measuring displacement of [3H]prazosin from rat brain cortex membranes (in vitro).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143697(8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227376(CHEMBL8689)
Affinity DataKi:  0.140nMAssay Description:Binding affinity towards alpha-1 adrenergic receptor from rat brain homogenate preparation by displacement of [3H]prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328500(CHEMBL1259144 | rac-N-((11-(4-Methylpiperazin-1-yl...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227298(CHEMBL147255)
Affinity DataKi:  0.150nMAssay Description:Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227290(CHEMBL148457)
Affinity DataKi:  0.150nMAssay Description:Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]prazosin (0.3 nM) from rat Alpha-1D adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328497((11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenzo[...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226234(CHEMBL50979)
Affinity DataKi:  0.160nMAssay Description:Binding affinity against alpha-1-adrenoceptor in rat brain homogenates [3H]-prazosin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.160nMAssay Description:Compound was tested for the inhibition of [3H]prazosin binding Alpha-1 adrenergic receptor of crude rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328501(CHEMBL1259145 | rac-N-((11-(4-Methylpiperazin-1-yl...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099325(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  0.170nMAssay Description:In vitro functional activity at Alpha-1B adrenergic receptor in rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226235(CHEMBL54288)
Affinity DataKi:  0.180nMAssay Description:Binding affinity against alpha-1-adrenoceptor in rat brain homogenates [3H]-prazosin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143666(8-{2-[4-(2-Chloro-5-fluoro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226227(CHEMBL52155)
Affinity DataKi:  0.180nMAssay Description:Binding affinity against alpha-1-adrenoceptor in rat brain homogenates [3H]-prazosin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity against alpha-1 adrenergic receptor by measuring displacement of [3H]prazosin from rat brain cortex membranes (in vitro).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.190nMAssay Description:In vitro binding affinity determined for alpha-1 adrenergic receptor by the displacement of [3H]- prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109058(1H-4-indolyl 2-[4-(1H-3-indolyl)-1,2,3,6-tetrahydr...)
Affinity DataKi:  0.190nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.190nMAssay Description:Compound was tested for its binding affinity for alpha-1 adrenergic receptor site by displacement of [3H]clonidine at 10e-6 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226233(CHEMBL275524)
Affinity DataKi:  0.190nMAssay Description:Binding affinity against alpha-1-adrenoceptor in rat brain homogenates [3H]-prazosin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity against alpha-1-adrenoceptor was determined by displacement of [3H]-prazosin in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity towards alpha-1 adrenergic receptor from rat brain homogenate preparation by displacement of [3H]prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226844(CHEMBL415288)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity determined for alpha-1 adrenergic receptor by the displacement of [3H]- prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143687(4-Chloro-2-{4-[2-(7,9-dioxo-8-aza-spiro[4.5]dec-8-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]prazosin (0.3 nM) from rat Alpha-1D adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity against alpha-1 adrenergic receptor by measuring displacement of [3H]prazosin from rat brain cortex membranes (in vitro).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50006952(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  0.210nMAssay Description:Alpha-1-adrenergic receptor binding affinity of the compound, value taken from literatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100238(7-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity of the compound to rat alpha-1D adrenergic receptor expressed in LTK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328506((S)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrod...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099322(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  0.213nMAssay Description:Binding affinity towards rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226846(CHEMBL6474)
Affinity DataKi:  0.220nMAssay Description:In vitro binding affinity determined for alpha-1 adrenergic receptor by the displacement of [3H]- prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099320(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  0.229nMAssay Description:Binding affinity towards rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007567(1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity by its ability to displace [3H]prazosin radioligand from Alpha-1 adrenergic receptor on rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]-prazosin from alpha1-adrenergic receptor in rat cerebral cortex membranes after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328488(5-(11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenz...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1755 total ) | Next | Last >>
Jump to: