Affinity DataKi: 20nMAssay Description:Binding affinity to Vanadate-sensitive ABCB1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:TP_TRANSPORTER: inhibition of Verapamil stimulated ATP hydrolysis in membranes from MDR1-expressing Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 100nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affini...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affini...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 134nMAssay Description:TP_TRANSPORTER: inhibition of ATPase activity (Verapamil) in P-gp-MRP-16-Protein A complexMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:TP_TRANSPORTER: inhibition of Hydroxydoxorubicin efflux in K562/Adr cellsMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Competitive inhibition of P-gp overexpressed in human MDA435/LCC6MDR cells assessed as accumulation of doxorubicin by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of human MDR1 transfected in mouse NIH/3T3 MDR1-G185 cells assessed as reduction in daunomycin accumulation after 30 mins by flow cytometr...More data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Competitive inhibition of P-gp overexpressed in human MDA435/LCC6MDR cells assessed as accumulation of doxorubicin by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:TP_TRANSPORTER: inhibition of Taxol transepithelial transport (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibition of human MDR1 transfected in mouse NIH/3T3 MDR1-G185 cells assessed as reduction in daunomycin accumulation after 30 mins by flow cytometr...More data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibition of human MDR1 overexpressed in mouse NIH/3T3 cells assessed as daunorubicin accumulation by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
