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Report error Found 24 of ic50 for UniProtKB: P21918
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM86180(NSC_5018 | CAS_87075-17-0 | SCH 23390 | SCH23390 |...)
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]SCH23390 from human recombinant Dopamine D5 receptor expressed in GH4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM86180(NSC_5018 | CAS_87075-17-0 | SCH 23390 | SCH23390 |...)
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]SCH 23390 from human recombinant D5 receptor expressed in GH4 cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 5nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 15nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50020221((-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen...)
Affinity DataIC50: 16nMAssay Description:Potency to displace the specific in vitro binding of [3H]-N-0437 to calf striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
LigandPNGBDBM29644(APOMORPHINE HYDROCHLORIDE | SMR000059235 | APOMORP...)
Affinity DataIC50: 25nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM50366495(CHEMBL1255588 | (+)butaclamol)
Affinity DataIC50: 50nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50: 500nMAssay Description:Inhibition of dopamine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105105({1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-y...)
Affinity DataIC50: 513nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105109(4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-c...)
Affinity DataIC50: 988nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50382290(RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50130841(CHEMBL3634745)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to dopamine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105102(4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-c...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105101(4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-c...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105107(1-{4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazin-1...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105103(1-{4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazin-1...)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105090(3-Methylcarbamoylmethyl-4-oxo-1-phenyl-1,3,8-triaz...)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50105061(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of human dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50223516(CHEMBL283871)
Affinity DataIC50: 8.00E+3nMAssay Description:Compound was evaluated for the competitive binding with [3H]spiperone binding to Canine striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50226008((R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL25040...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50304075(3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50176440(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at Gs-coupled human D5R expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed