Affinity DataIC50: 0.210nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of TOP2A in human 90-8TL cells assessed as reduction in cell viability at 1 to 500 ng/ml incubated for 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of TOP2A in human ST88-14 cells assessed as reduction in cell viability at 1 to 500 ng/ml incubated for 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of TOP2A in human STS26T cells assessed as reduction in cell viability at 1 to 500 ng/ml incubated for 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of TOP2A in human T265 cells assessed as reduction in cell viability at 1 to 500 ng/ml incubated for 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Induction of poison effect at DNA topoisomerase 2 by G-quadruplex interaction polymerase stop assayMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibition of TOP2A in human SNF96.2 cells assessed as reduction in cell viability at 1 to 500 ng/ml incubated for 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of Homo sapiens (human) topoisomerase 2 assessed as decatenation of KDNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of Homo sapiens (human) DNA topoisomerase 2More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Topo IIalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 592nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 592nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human topoisomerase-2alpha using catenated DNA as substrate after 30 mins by ethidium bromide-based gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 639nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Induction of poison effect at DNA topoisomerase 2 by G-quadruplex interaction polymerase stop assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 850nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of purified human topoisomerase 2-mediated relaxation of supercoiled pBR322 DNA at 50 uM incubated for 30 mins in presence of 1 mM ATP by ...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of human topoisomerase-2alpha assessed as reduction in enzyme-mediated decatenation using kinetoplast DNA as substrate after 15 mins by et...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition human placenta topoisomerase 2 assessed as conversion of catenated kinetoplast DNA to minicircle monomerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition human placenta topoisomerase 2 assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of DNA topoisomerase 2 alpha (unknown origin) measured by topoisomerase-mediated DNA relaxation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 deletion mutant assessed as ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of DNA topoisomerase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair




































