Compile Data Set for Download or QSAR
Report error Found 147 of ki for UniProtKB: Q13255
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50301822(CHEMBL568443 | CHEMBL1645349 | 5-(1-(2-fluoropyrid...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50301822(CHEMBL568443 | CHEMBL1645349 | 5-(1-(2-fluoropyrid...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50333368([11C]-cis-(3-ethyl-2-methylquinolin-6-yl)(4-methox...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50333368([11C]-cis-(3-ethyl-2-methylquinolin-6-yl)(4-methox...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(CHEMBL502882 | CHEMBL1645350 | 4-[1-(2-Fuluoropyri...)
Affinity DataKi:  2nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50273942(CHEMBL502882 | CHEMBL1645350 | 4-[1-(2-Fuluoropyri...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50333371(CHEMBL1645351 | CHEMBL1771388 | [11C]-6-N-cyclohex...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to mGluR1 by PET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50333371(CHEMBL1645351 | CHEMBL1771388 | [11C]-6-N-cyclohex...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM86716(NSC_216215 | CAS_63540-28-3 | CHEMBL239800 | Fenob...)
Affinity DataKi:  6.70nMAssay Description:Antagonist activity at human mGLUR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataKi:  36nMAssay Description:Antagonist activity at human mGLUR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50296665(Adamantan-1-yl-[2-(6-morpholin-4-yl-2-pyridin-3-yl...)
Affinity DataKi:  110nMAssay Description:Binding affinity to human GluR1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089912((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...)
Affinity DataKi:  150nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]quisqualate from mGluR1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50013055(glutamic acid dianion | 2-aminopentanedioateglutam...)
Affinity DataKi:  340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089909(3-[1-Amino-1-carboxy-2-(9H-thioxanthen-9-yl)-ethyl...)
Affinity DataKi:  350nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM85706(2Me4CPG)
Affinity DataKi:  700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM85707(CAS_82410-32-0 | NSC_3454 | DHPG)
Affinity DataKi:  900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataKi:  1.10E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089906(2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid...)
Affinity DataKi:  1.60E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50050919(7HCCMA | CHEMBL74231 | (1S,2S,3R)-2-(Amino-carboxy...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50004899(L-CCG-IV | 2-(Amino-carboxy-methyl)-cyclopropaneca...)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50004863(1S, 3R-ACPD | CHEMBL29726 | 1R,3R-ACPD | 1R,3S-ACP...)
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50004899(L-CCG-IV | 2-(Amino-carboxy-methyl)-cyclopropaneca...)
Affinity DataKi:  3.47E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM82251((S)-4CPG | CAS_134052-68-9 | (R)-4-Carboxyphenylgl...)
Affinity DataKi:  3.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089905(4-[1-Amino-1-carboxy-2-(9H-thioxanthen-9-yl)-ethyl...)
Affinity DataKi:  5.70E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089913(4-(Amino-carboxy-methyl)-2-hydroxy-3-methyl-benzoi...)
Affinity DataKi:  6.00E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50079183(amino(3,5-dihydroxyphenyl)acetic acid | 3,5-DHPG |...)
Affinity DataKi:  6.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50079183(amino(3,5-dihydroxyphenyl)acetic acid | 3,5-DHPG |...)
Affinity DataKi:  6.60E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-...)
Affinity DataKi:  6.80E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50030630(AIDA | AIDC | 1-Amino-indan-1,5-dicarboxylic acid(...)
Affinity DataKi:  7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089896(CHEMBL315591 | LY367385 | 4-(Amino-carboxy-methyl)...)
Affinity DataKi:  8.80E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  9.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | NSC_5126051 | CPCCOEt)
Affinity DataKi:  9.90E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50215552(3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethyny...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50031703(2-Amino-4-methyl-pentanedioic acid(S-Me-Glu) | (2S...)
Affinity DataKi:  1.00E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50053586(3C4HPG | CHEMBL128772 | 5-((S)-Amino-carboxy-methy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM85017((1S,3S)-HOMO-ACPD | (1S,3S)-1-AMINO-1-CARBOXYCYCLO...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50030629(4-(Amino-carboxy-methyl)-benzoic acid | (S)-4CPG |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | 3HPG | CHEMBL442347 |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50030628(CHEMBL444589 | 4-(Amino-carboxy-methyl)-2-hydroxy-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50076394(ABHD-I | CHEMBL39215 | 2-Amino-bicyclo[2.2.1]hepta...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50030627(CHEMBL299683 | MCPG | (R,S)-alpha-Methyl-4-carboxy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50089910(CHEMBL86508 | MPPG | 2-Amino-2-(4-phosphono-phenyl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
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