Compile Data Set for Download or QSAR
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557828(US11365185, Example 10B | 1-[4-[6-[5-[[6-(cyclopro...)
Affinity DataKi:  12.5nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557838(US11365185, Example 20B | 1-[4-[6-[5-[(6-isopropox...)
Affinity DataKi:  12.7nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557845(US11365185, Example 27B)
Affinity DataKi:  15.3nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146232(Phosphoric acid mono-{(R)-2-((Z)-octadec-9-enoylam...)
Affinity DataKi:  18nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146232(Phosphoric acid mono-{(R)-2-((Z)-octadec-9-enoylam...)
Affinity DataKi:  18nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557844(US11365185, Example 26B | 1-[4-[4-[5-[(6-isopropyl...)
Affinity DataKi:  18.8nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50150007(Phosphoric acid mono-((R)-2-((Z)-octadec-9-enoylam...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557836(US11365185, Example 18B | 1-[4-[2-[5-[(6-isopropyl...)
Affinity DataKi:  24.5nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50149996(Phosphoric acid mono-[3-[4-(4-ethoxy-pyridin-2-ylm...)
Affinity DataKi:  26nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557839(US11365185, Example 21B | 1-[4-[6-[1-methyl-5-[[6-...)
Affinity DataKi:  27.6nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557831(US11365185, Example 13B | 1-[4-[6-[5-[[6-(1-fluoro...)
Affinity DataKi:  28nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50149997(Phosphoric acid mono-[3-[4-(4-methoxy-3,5-dimethyl...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557843(US11365185, Example 25B)
Affinity DataKi:  30.8nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146240(Phosphoric acid mono-[(R)-3-[4-(3-methoxy-benzylox...)
Affinity DataKi:  34nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557829(US11365185, Example 11B | 1-[4-[5-fluoro-6-[5-[(6-...)
Affinity DataKi:  34.6nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50150000(Phosphoric acid mono-[(R)-3-{4-[4-(2-methoxy-ethox...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557830(US11365185, Example 12B | 1-[4-[6-[5-[[6-(1,1-difl...)
Affinity DataKi:  40.9nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557821(US11365185, Example 3B | 1-[4-[6-[5-[[6-(cycloprop...)
Affinity DataKi:  44.2nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557842(US11365185, Example 24B)
Affinity DataKi:  46.2nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataKi:  48nMAssay Description:Binding affinity to LPA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50271763(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)
Affinity DataKi:  50nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557823(US11365185, Example 5B | 1-[4-[6-[5-[[6-(3,3-diflu...)
Affinity DataKi:  51.4nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557834(US11365185, Example 16B | 1-[3-cyano-4-[6-[5-[(6-i...)
Affinity DataKi:  53.8nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50193515(1-fluoro-(3S)-hydroxyl-4-oleoyloxylbutane 1,3-cycl...)
Affinity DataKi:  60.7nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50150014(Phosphoric acid mono-{2-((Z)-(R)-octadec-9-enoylam...)
Affinity DataKi:  64nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557825(US11365185, Example 7B | 1-[4-[6-[5-[(6-isopropoxy...)
Affinity DataKi:  72.3nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146238(Phosphoric acid mono-[(R)-3-[4-(1H-indol-2-yloxy)-...)
Affinity DataKi:  73nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557822(US11365185, Example 4B | 1-[4-[5-fluoro-6-[5-[[6-(...)
Affinity DataKi:  80.5nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50496698(CHEMBL3218459)
Affinity DataKi:  84nMAssay Description:Competitive antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557833(US11365185, Example 15B | 1-[3-(cyanomethyl)-4-[6-...)
Affinity DataKi:  94.8nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557824(US11365185, Example 6B | 1-[4-[6-[5-[[6-(1-methoxy...)
Affinity DataKi:  115nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146250(Phosphoric acid mono-[(R)-3-[4-(indan-2-yloxy)-phe...)
Affinity DataKi:  134nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146237(Phosphoric acid mono-[3-(4-benzyloxy-phenyl)-2-((Z...)
Affinity DataKi:  137nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50176398((S)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosp...)
Affinity DataKi:  139nMAssay Description:Activity at LPA1 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50496697(CHEMBL3218460)
Affinity DataKi:  143nMAssay Description:Competitive antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146230(Phosphoric acid mono-{(S)-2-((Z)-octadec-9-enoylam...)
Affinity DataKi:  156nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146230(Phosphoric acid mono-{(S)-2-((Z)-octadec-9-enoylam...)
Affinity DataKi:  156nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50176393(octanoic acid (S)-2-octanoyloxy-3-phosphonooxy-pro...)
Affinity DataKi:  221nMAssay Description:Activity at LPA1 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50304581(2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic ...)
Affinity DataKi:  311nMAssay Description:Binding affinity to LPA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50193518(3-hydroxyl-4-palmitoyloxylbutane 1,3-cyclic phosph...)
Affinity DataKi:  314nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50146248(Phosphoric acid mono-[(S)-3-[4-(3-methoxy-benzylox...)
Affinity DataKi:  358nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50176394(octanoic acid (R)-2-octanoyloxy-3-thiophosphonooxy...)
Affinity DataKi:  360nMAssay Description:Activity at LPA1 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50193517(3-hydroxyl-4-oleoyloxylbutane 1,3-cyclic phosphono...)
Affinity DataKi:  403nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50176391(octanoic acid (R)-2-octanoyloxy-3-phosphonooxy-pro...)
Affinity DataKi:  407nMAssay Description:Activity at LPA1 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50170859(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonylamino)-...)
Affinity DataKi:  425nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50170851(Phosphoric acid mono-((E)-tetradec-11-enyl) ester ...)
Affinity DataKi:  457nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50170861((1,1-Difluoro-pentadecyl)-phosphonic acid | CHEMBL...)
Affinity DataKi:  788nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50170842(Phosphoric acid monotetradecyl ester | CHEMBL18763...)
Affinity DataKi:  1.08E+3nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50170843(Phosphoric acid mono-((E)-tetradec-9-enyl) ester |...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM50170854(Phosphoric acid monododecyl ester | CHEMBL187711)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 1 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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