Compile Data Set for Download or QSAR
Found 4551 of ic50 for UniProtKB: Q92793
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537094(US11247989, Example 92)
Affinity DataIC50:  0.760nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50453957(CHEMBL4217213)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant His-tagged CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537100(US11247989, Example 93)
Affinity DataIC50:  0.910nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  0.940nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536872(1-(1-acetylpiperidin-4-yl)-N-methyl-3-(3-(2-methyl...)
Affinity DataIC50:  0.970nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataIC50:  0.997nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511356(N-methyl-1-(3-(6- (methylcarbamoyl)pyridin- 3-yl)i...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM340734(3-[5-(difluoromethyl)-2-fluoro-4-(1-methylpyrazol-...)
Affinity DataIC50:  1nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269857(CHEMBL4088793)
Affinity DataIC50:  1nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269848(CHEMBL4069831)
Affinity DataIC50:  1nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511322(3-Cyclopropyl-N-methyl-1-(3-(2-methylthiazol-5-yl)...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511316(3-Cyclopropyl-N-methyl-1-(3-(6-(methylcarbamoyl)py...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511394(3-(4,4- difluorocyclohexyl)-1-(7- fluoro-3-(2-meth...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511390(1-(7-fluoro-3-(2- methylthiazol-5- yl)isoquinolin-...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511377(3-(4,4- difluorocyclohexyl)-N- methyl-1-(2-(1-meth...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM340748(US9763922, Example 274)
Affinity DataIC50:  1nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537101(US11247989, Example 94)
Affinity DataIC50:  1nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536819(3-(6-(difluoromethyl)-7-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  1.07nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269849(CHEMBL4076748)
Affinity DataIC50:  1.10nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537087(US11247989, Example 90)
Affinity DataIC50:  1.10nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536735(US11247989, Example 9)
Affinity DataIC50:  1.13nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536741(US11247989, Example 10)
Affinity DataIC50:  1.15nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50453950(CHEMBL4203082 | US11247989, Example 88)
Affinity DataIC50:  1.16nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537088(US11247989, Example 91)
Affinity DataIC50:  1.17nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant His-tagged CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50453950(CHEMBL4203082 | US11247989, Example 88)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant His-tagged CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269856(CHEMBL4060566)
Affinity DataIC50:  1.20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269855(CHEMBL4061161)
Affinity DataIC50:  1.20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536862((S)-1-(3-(6-(1-methyl-1H-pyrazol-4-yl)naphthalen-1...)
Affinity DataIC50:  1.39nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269850(CHEMBL4061600)
Affinity DataIC50:  1.40nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536875(2-cyano-N-methyl-3-(3-(1-methyl-1H-pyrazol-4-yl)is...)
Affinity DataIC50:  1.42nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536860(N-methyl-3-(4-methyl-3-(1-methyl-1H-pyrazol-4-yl)i...)
Affinity DataIC50:  1.45nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269907(CHEMBL4080905)
Affinity DataIC50:  1.5nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269914(CHEMBL4083416)
Affinity DataIC50:  1.5nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50602881(CHEMBL5204688)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536871(N-methyl-3-(3-(2-methylthiazol-5-yl)isoquinolin-8-...)
Affinity DataIC50:  1.54nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536857(1-(3-(6-ethyl-3-(1-methyl-1H-pyrazol-4-yl)isoquino...)
Affinity DataIC50:  1.71nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537149(US11247989, Example 129)
Affinity DataIC50:  1.85nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50602873(CHEMBL5191045)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM536873(3-isopropyl-N-methyl-1-(3-(1-methyl-1H-pyrazol-4-y...)
Affinity DataIC50:  1.91nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM537086(US11247989, Example 89)
Affinity DataIC50:  1.92nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511379(3-(4,4- difluorocyclohexyl)-N- methyl-1-(3-(1-meth...)
Affinity DataIC50:  2nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM340746(US9763922, Example 272)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM340740(US9763922, Example 266)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM340730(3-[5-(difluoromethyl)-2-fluoro-4-(1-methylpyrazol-...)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM340716(1-[3-[5-(difluoromethyl)-2-fluoro-4-(1-methylpyraz...)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50269906(CHEMBL4098938)
Affinity DataIC50:  2nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM448593(5-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM50250892(CHEMBL4061254 | US10696655, Example 63 | US1116807...)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM448659(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  2nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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