Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 7902
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKi:  640nM ΔG°:  -35.4kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223301(120H10)
Affinity DataKi:  960nM ΔG°:  -34.3kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223310(123C7)
Affinity DataKi:  1.59E+3nM ΔG°:  -33.1kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223305(123C2)
Affinity DataKi:  1.59E+3nM ΔG°:  -33.1kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223300(EphA4-LBC inhibitor, Compound 22)
Affinity DataKi:  2.14E+3nM ΔG°:  -32.4kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223307(123C3)
Affinity DataKi:  2.22E+3nM ΔG°:  -32.3kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223308(123C5)
Affinity DataKi:  2.57E+3nM ΔG°:  -31.9kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223302(123B1)
Affinity DataKi:  3.04E+3nM ΔG°:  -31.5kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223309(123C6)
Affinity DataKi:  3.14E+3nM ΔG°:  -31.4kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223306(123C12)
Affinity DataKi:  7.67E+3nM ΔG°:  -29.2kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223303(120G1)
Affinity DataKi:  1.40E+4nM ΔG°:  -27.7kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223304(120G2)
Affinity DataKi:  1.00E+5nM ΔG°:  -22.8kJ/molepH: 7.2 T: 2°CAssay Description:For competitive binding assays, 1 mL of 200 mM EphA4-LBD was pre-incubated with the tested compounds at various concentrations in 98 mL of PBS (pH 7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,M164A](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  62nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,M60A](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  350nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,I159A](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  290nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,I67A](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  780nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,I59A](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  9.09E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,I59G](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  3.66E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3 [29-207](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  4.55E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  420nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223310(123C7)
Affinity DataKd:  540nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223308(123C5)
Affinity DataKd:  2.20E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223305(123C2)
Affinity DataKd:  1.10E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209,D61G,E62G](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223311(123C4)
Affinity DataKd:  340nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 4 [29-209](Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

LigandPNGBDBM223300(EphA4-LBC inhibitor, Compound 22)
Affinity DataKd:  1.20E+3nMpH: 6.5 T: 2°CAssay Description:The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed