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Found 24 Enz. Inhib. hit(s) with all data for entry = 50029459
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284744(3-Allyloxycarbonylamino-5-[3-(1H-imidazol-2-yl)-na...)
Affinity DataKi:  90nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284735(3-Allyloxycarbonylamino-5-(3-carbamoyl-naphthalen-...)
Affinity DataKi:  320nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284734(3-Allyloxycarbonylamino-4-oxo-5-(3-phenylcarbamoyl...)
Affinity DataKi:  500nMAssay Description:Binding affinity determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284733(3-Allyloxycarbonylamino-5-(3-cyano-naphthalen-2-yl...)
Affinity DataKi:  620nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284740(3-Allyloxycarbonylamino-5-(3-hydroxymethyl-naphtha...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50213208(CHEMBL3143890)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284745(3-Allyloxycarbonylamino-5-(4-carbamoyl-biphenyl-3-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284741(3-(3-Allyloxycarbonylamino-4-carboxy-2-oxo-butoxy)...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284743(3-Allyloxycarbonylamino-4-oxo-5-phenoxy-pentanoic ...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284748(3-Allyloxycarbonylamino-5-(2-carbamoyl-phenoxy)-4-...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284749(3-Allyloxycarbonylamino-5-(naphthalen-2-yloxy)-4-o...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284739(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284747(3-Allyloxycarbonylamino-5-(naphthalen-1-yloxy)-4-o...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284737(3-Allyloxycarbonylamino-5-(1-carbamoyl-naphthalen-...)
Affinity DataKi: >1.80E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284736(3-Allyloxycarbonylamino-5-(2-carbamoyl-naphthalen-...)
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284738(3-Allyloxycarbonylamino-5-(3-dimethylcarbamoyl-nap...)
Affinity DataKi: >2.80E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284746(3-Allyloxycarbonylamino-6-[3-(1H-imidazol-2-yl)-na...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284733(3-Allyloxycarbonylamino-5-(3-cyano-naphthalen-2-yl...)
Affinity DataKoff:  4.50E+3s-1Assay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284739(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKoff:  1.10s-1Assay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50450287(CHEMBL31061)
Affinity DataKoff:  3.40E+3s-1Assay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50213208(CHEMBL3143890)
Affinity DataKoff:  4.30s-1Assay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284744(3-Allyloxycarbonylamino-5-[3-(1H-imidazol-2-yl)-na...)
Affinity DataKoff:  1.20E+4s-1Assay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284735(3-Allyloxycarbonylamino-5-(3-carbamoyl-naphthalen-...)
Affinity DataKoff:  5.60E+3s-1Assay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284734(3-Allyloxycarbonylamino-4-oxo-5-(3-phenylcarbamoyl...)
Affinity DataKoff:  4.10E+3s-1Assay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
In DepthDetails Article