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Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50010384
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi:  0.430nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  9.42nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50029644(CHEMBL296908 | N-(3-(4-(4-(2-oxo-3,4-dihydroquinol...)
Affinity DataKi:  32nMAssay Description:Binding affinity of the compound towards Vasopressin V1a receptor in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50029644(CHEMBL296908 | N-(3-(4-(4-(2-oxo-3,4-dihydroquinol...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity of the compound towards Vasopressin V1a receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  0.950nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094079((4-Amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrah...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094068((2-Chloro-4-ethylamino-phenyl)-(7-chloro-2,3,4,5-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094086((4-Allylamino-2-chloro-phenyl)-(2,3,4,5-tetrahydro...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094082((2-Chloro-4-pyrrol-1-yl-phenyl)-(2,3,4,5-tetrahydr...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094066((2-Chloro-4-pyrazol-1-yl-phenyl)-(2,3,4,5-tetrahyd...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094075((2-Chloro-4-pyrrolidin-1-yl-phenyl)-(2,3,4,5-tetra...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094074((2-Chloro-4-dimethylamino-phenyl)-(7-chloro-2,3,4,...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094070(CHEMBL136109 | [2-Chloro-4-(3-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094072((2-Chloro-4-pyrrolidin-1-yl-phenyl)-(7-chloro-2,3,...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094067((2-Chloro-4-dimethylamino-phenyl)-(2,3,4,5-tetrahy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094089((2-Chloro-4-propylamino-phenyl)-(2,3,4,5-tetrahydr...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094077((2-Chloro-4-diethylamino-phenyl)-(2,3,4,5-tetrahyd...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094078((4-Butylamino-2-chloro-phenyl)-(2,3,4,5-tetrahydro...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094087((2-Chloro-4-pentylamino-phenyl)-(2,3,4,5-tetrahydr...)
Affinity DataIC50:  31nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094069((2-Chloro-4-ethylamino-phenyl)-(2,3,4,5-tetrahydro...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094083((2-Chloro-4-methylamino-phenyl)-(2,3,4,5-tetrahydr...)
Affinity DataIC50:  35nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  38nMAssay Description:Binding affinity of the compound towards rat Vasopressin V2 receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094088(CHEMBL136790 | [2-Chloro-4-(3-methyl-pyrrolidin-1-...)
Affinity DataIC50:  51nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094073((2-Chloro-4-piperidin-1-yl-phenyl)-(2,3,4,5-tetrah...)
Affinity DataIC50:  120nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094075((2-Chloro-4-pyrrolidin-1-yl-phenyl)-(2,3,4,5-tetra...)
Affinity DataIC50:  150nMAssay Description:Binding affinity of the compound towards rat Vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094081((4-Amino-phenyl)-(2,3,4,5-tetrahydro-benzo[b]azepi...)
Affinity DataIC50:  180nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094080((7-Chloro-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094085((4-Pyrrol-1-yl-phenyl)-(2,3,4,5-tetrahydro-benzo[b...)
Affinity DataIC50:  320nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094084((4-Pyrrolidin-1-yl-phenyl)-(2,3,4,5-tetrahydro-ben...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  5.10E+3nMAssay Description:Binding affinity of the compound towards rat Vasopressin V1a receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed