Compile Data Set for Download or QSAR
Report error Found 124 Enz. Inhib. hit(s) with all data for entry = 50045439
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062621(CHEMBL3397710)
Affinity DataEC50:  1.41E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062719(CHEMBL3397709)
Affinity DataEC50:  1.56E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062721(CHEMBL3397724)
Affinity DataEC50:  3.77E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062722(CHEMBL3397726)
Affinity DataEC50:  1.26E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062722(CHEMBL3397726)
Affinity DataEC50:  1.12E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062726(CHEMBL3397727)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062723(CHEMBL3397728)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50273683(2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic aci...)
Affinity DataEC50:  8.30E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50322460(2-(4,6-Bis(2-cyclohexylethoxy)pyrimidin-2-ylthio)h...)
Affinity DataEC50:  6.60E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062719(CHEMBL3397709)
Affinity DataEC50:  720nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062720(CHEMBL3397708)
Affinity DataEC50:  1.20E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062726(CHEMBL3397727)
Affinity DataEC50:  2.16E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50396066(CHEMBL1819479)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062621(CHEMBL3397710)
Affinity DataEC50:  1.17E+4nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062718(CHEMBL3397711)
Affinity DataEC50:  1.29E+4nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50322460(2-(4,6-Bis(2-cyclohexylethoxy)pyrimidin-2-ylthio)h...)
Affinity DataEC50:  4.60E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062731(CHEMBL3397717)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062732(CHEMBL3397718)
Affinity DataEC50:  2.32E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062733(CHEMBL3397719)
Affinity DataEC50:  2.10E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50273683(2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic aci...)
Affinity DataEC50:  1.13E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062728(CHEMBL3397720)
Affinity DataEC50:  1.07E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062727(CHEMBL3397721)
Affinity DataEC50:  1.17E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062729(CHEMBL3397715)
Affinity DataEC50:  5.17E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062730(CHEMBL3397716)
Affinity DataEC50:  2.11E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062731(CHEMBL3397717)
Affinity DataEC50:  4.64E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062732(CHEMBL3397718)
Affinity DataEC50:  2.56E+3nMAssay Description:Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062730(CHEMBL3397716)
Affinity DataEC50:  3.20E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062729(CHEMBL3397715)
Affinity DataEC50:  1.38E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062734(CHEMBL3397714)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062725(CHEMBL3397722)
Affinity DataEC50:  2.20E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062724(CHEMBL3397723)
Affinity DataEC50:  4.50E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062735(CHEMBL3397713)
Affinity DataEC50:  3.20E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062721(CHEMBL3397724)
Affinity DataEC50:  970nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062619(CHEMBL3397725)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062736(CHEMBL3397712)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062718(CHEMBL3397711)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50396066(CHEMBL1819479)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062727(CHEMBL3397721)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062724(CHEMBL3397723)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062722(CHEMBL3397726)
Affinity DataIC50: 250nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062730(CHEMBL3397716)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062731(CHEMBL3397717)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062723(CHEMBL3397728)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062729(CHEMBL3397715)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062621(CHEMBL3397710)
Affinity DataIC50: 550nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50273683(2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic aci...)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062727(CHEMBL3397721)
Affinity DataIC50: 630nMAssay Description:Inhibition of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062733(CHEMBL3397719)
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062718(CHEMBL3397711)
Affinity DataIC50: 750nMAssay Description:Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50062731(CHEMBL3397717)
Affinity DataIC50: 790nMAssay Description:Inhibition of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
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