Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50027278
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253155(N-Cyclopropyl-4-methyl-3-(4-(1-methylethoxy)-7-iso...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(N-Cyclopropyl-4-methyl-3-(1-(1-methylethoxy)-6-pht...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(N-Cyclopropyl-4-methyl-3-(1-((3S)-3-methyl-4-morph...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252740(N-Cyclopropyl-4-methyl-3-(1-((2-(4-morpholino)ethy...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(N-Cyclopropyl-4-methyl-3-(1-phenyl-6-phthalazinyl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 10.5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253155(N-Cyclopropyl-4-methyl-3-(4-(1-methylethoxy)-7-iso...)
Affinity DataIC50: 41nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 122nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253153(N-Cyclopropyl-4-methyl-3-(1-phenyl-6-phthalazinyl)...)
Affinity DataIC50: 149nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 162nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 182nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252781(N-Cyclopropyl-4-methyl-3-(1-(1-methylethoxy)-6-pht...)
Affinity DataIC50: 421nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 505nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 529nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 629nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 788nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 954nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252740(N-Cyclopropyl-4-methyl-3-(1-((2-(4-morpholino)ethy...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252781(N-Cyclopropyl-4-methyl-3-(1-(1-methylethoxy)-6-pht...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(N-Cyclopropyl-4-methyl-3-(1-phenyl-6-phthalazinyl)...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252779(N-Cyclopropyl-4-methyl-3-(1-((3S)-3-methyl-4-morph...)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(N-Cyclopropyl-4-methyl-3-(1-(1-methylethoxy)-6-pht...)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(N-Cyclopropyl-4-methyl-3-(1-((3S)-3-methyl-4-morph...)
Affinity DataIC50: 4.83E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252740(N-Cyclopropyl-4-methyl-3-(1-((2-(4-morpholino)ethy...)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(N-Cyclopropyl-4-methyl-3-(1-(1-methylethoxy)-6-pht...)
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253153(N-Cyclopropyl-4-methyl-3-(1-phenyl-6-phthalazinyl)...)
Affinity DataIC50: 6.29E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 6.63E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252779(N-Cyclopropyl-4-methyl-3-(1-((3S)-3-methyl-4-morph...)
Affinity DataIC50: 8.55E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 9.49E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 9.69E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(N-Cyclopropyl-4-methyl-3-(1-((3S)-3-methyl-4-morph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252740(N-Cyclopropyl-4-methyl-3-(1-((2-(4-morpholino)ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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